PJA1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PJA1 at tissue level.

III. Associated gene sets

GO_0030163Biological processprotein catabolic process
GO_0005737Cellular componentcytoplasm
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePJA1
Protein namePraja ring finger ubiquitin ligase 1
PJA1 protein
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
SynonymsRNF70
DescriptionFUNCTION: Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting. .

AccessionsENST00000374584.3 [Q8NG27-2]
Q8NG27
ENST00000374571.5 [Q8NG27-3]
K7EPI8
ENST00000471141.1
ENST00000361478.1 [Q8NG27-1]
A4FUA0
K7EPW5
ENST00000590146.1
ENST00000374583.1 [Q8NG27-1]