PIGK | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	7 studies	27% ± 9%	Explore
endothelial cell	4 studies	19% ± 3%	Explore
epithelial cell	4 studies	23% ± 7%	Explore
GABAergic neuron	3 studies	46% ± 4%	Explore
glutamatergic neuron	3 studies	60% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	22% ± 4%	Explore
astrocyte	3 studies	30% ± 17%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	45% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	1713.06	459 / 459	100%	30.03	1117 / 1118
ovary	100%	1376.87	180 / 180	100%	15.77	429 / 430
brain	100%	1412.14	2635 / 2642	100%	20.16	705 / 705
lung	100%	1490.30	577 / 578	100%	20.41	1153 / 1155
esophagus	100%	1115.91	1439 / 1445	100%	20.09	183 / 183
prostate	100%	1149.27	244 / 245	100%	28.55	500 / 502
thymus	100%	1683.73	653 / 653	99%	24.44	600 / 605
uterus	99%	1516.38	169 / 170	99%	21.91	456 / 459
adrenal gland	100%	1540.67	258 / 258	99%	25.77	227 / 230
kidney	100%	1538.80	89 / 89	99%	25.42	889 / 901
intestine	100%	1358.75	966 / 966	98%	17.19	518 / 527
stomach	100%	1087.52	359 / 359	98%	18.80	281 / 286
bladder	100%	1379.19	21 / 21	98%	16.76	494 / 504
skin	99%	1784.07	1796 / 1809	97%	28.30	460 / 472
pancreas	98%	769.41	320 / 328	99%	19.52	176 / 178
liver	99%	741.33	223 / 226	96%	13.11	388 / 406
blood vessel	100%	2655.85	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	12.17	29 / 29
spleen	100%	1245.55	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	19.00	45 / 45
ureter	0%	0	0 / 0	100%	5.35	1 / 1
adipose	100%	1606.05	1203 / 1204	0%	0	0 / 0
muscle	99%	780.00	793 / 803	0%	0	0 / 0
heart	97%	1394.78	838 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	13.78	72 / 80
peripheral blood	79%	689.99	731 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0016255	Biological process	attachment of GPI anchor to protein
GO_0006508	Biological process	proteolysis
GO_0042765	Cellular component	GPI-anchor transamidase complex
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0003756	Molecular function	protein disulfide isomerase activity
GO_0034235	Molecular function	GPI anchor binding
GO_0005515	Molecular function	protein binding
GO_0003923	Molecular function	GPI-anchor transamidase activity

Gene name	PIGK
Protein name	GPI-anchor transamidase (Phosphatidylinositol-glycan biosynthesis class K protein) GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) Phosphatidylinositol glycan anchor biosynthesis class K
Synonyms	hCG_22810 GPI8
Description	FUNCTION: Component of the GPI transamidase complex, necessary for transfer of GPI to proteins . Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. .
Accessions	B1AK81 ENST00000359130.1 S4R3M5 ENST00000445065.5 ENST00000370812.8 [Q92643-1] A6NEM5 ENST00000487906.5 Q92643

PIGK report