PHOSPHO1 | OmnibusX

Name	Number of supported studies	Average coverage
erythrocyte	4 studies	32% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PHOSPHO1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	89%	131.44	2357 / 2642	73%	2.33	516 / 705
kidney	85%	85.84	76 / 89	62%	1.54	562 / 901
lung	99%	222.81	572 / 578	42%	1.17	490 / 1155
adrenal gland	84%	61.79	217 / 258	33%	2.77	75 / 230
prostate	86%	78.10	210 / 245	22%	0.37	108 / 502
spleen	100%	829.49	241 / 241	0%	0	0 / 0
thymus	76%	65.85	499 / 653	23%	0.45	140 / 605
peripheral blood	98%	10574.35	912 / 929	0%	0	0 / 0
ovary	17%	11.42	30 / 180	77%	7.57	330 / 430
esophagus	39%	27.90	563 / 1445	50%	1.15	92 / 183
uterus	61%	46.18	103 / 170	28%	1.02	130 / 459
intestine	50%	42.17	485 / 966	37%	0.82	193 / 527
stomach	33%	22.09	120 / 359	51%	1.14	146 / 286
muscle	78%	154.53	627 / 803	0%	0	0 / 0
breast	58%	40.02	266 / 459	19%	0.60	214 / 1118
heart	75%	60.90	649 / 861	0%	0	0 / 0
adipose	66%	64.39	797 / 1204	0%	0	0 / 0
bladder	38%	24.76	8 / 21	22%	0.55	110 / 504
tonsil	0%	0	0 / 0	58%	1.35	26 / 45
liver	46%	29.95	103 / 226	4%	0.06	16 / 406
lymph node	0%	0	0 / 0	48%	3.08	14 / 29
pancreas	5%	3.88	17 / 328	43%	0.77	76 / 178
skin	14%	8.86	250 / 1809	13%	0.22	62 / 472
blood vessel	24%	20.77	325 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	9%	0.13	7 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030500	Biological process	regulation of bone mineralization
GO_0035630	Biological process	bone mineralization involved in bone maturation
GO_0001958	Biological process	endochondral ossification
GO_0030282	Biological process	bone mineralization
GO_0065010	Cellular component	extracellular membrane-bounded organelle
GO_0005829	Cellular component	cytosol
GO_0031012	Cellular component	extracellular matrix
GO_0052732	Molecular function	phosphoethanolamine phosphatase activity
GO_0016791	Molecular function	phosphatase activity
GO_0016462	Molecular function	pyrophosphatase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0052731	Molecular function	phosphocholine phosphatase activity

Gene name	PHOSPHO1
Protein name	Phosphoethanolamine/phosphocholine phosphatase 1 Phosphoethanolamine/phosphocholine phosphatase (EC 3.1.3.75)
Synonyms
Description	FUNCTION: Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho) . Involved in the generation of inorganic phosphate for bone mineralization (By similarity). Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix (By similarity). .
Accessions	D6RHH9 ENST00000503902.1 D6RB58 Q8TCT1 ENST00000512250.1 ENST00000514112.1 [Q8TCT1-3] ENST00000413580.5 [Q8TCT1-3] I3L4N1 ENST00000574638.1 D6RIT6 ENST00000310544.9 [Q8TCT1-1] ENST00000511066.5

PHOSPHO1 report