PHKA2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0005975Biological processcarbohydrate metabolic process
GO_0006091Biological processgeneration of precursor metabolites and energy
GO_0036211Biological processprotein modification process
GO_0005977Biological processglycogen metabolic process
GO_0005964Cellular componentphosphorylase kinase complex
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005516Molecular functioncalmodulin binding
GO_0004689Molecular functionphosphorylase kinase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePHKA2
Protein namePhosphorylase kinase alpha-subunit (EC 2.7.1.38)
Phosphorylase b kinase regulatory subunit alpha, liver isoform (Phosphorylase kinase alpha L subunit)
SynonymsPHKLA
PYK
DescriptionFUNCTION: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

AccessionsO60912
P46019
ENST00000379942.5