PGP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006650Biological processglycerophospholipid metabolic process
GO_0006114Biological processglycerol biosynthetic process
GO_0045721Biological processnegative regulation of gluconeogenesis
GO_0005737Cellular componentcytoplasm
GO_0000121Molecular functionglycerol-1-phosphatase activity
GO_0008967Molecular functionphosphoglycolate phosphatase activity
GO_0043136Molecular functionglycerol-3-phosphatase activity
GO_0043262Molecular functionADP phosphatase activity
GO_0000287Molecular functionmagnesium ion binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene namePGP
Protein nameGlycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP)
Phosphoglycolate phosphatase
Synonyms
DescriptionFUNCTION: Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear . In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity). .

AccessionsA6NDG6
H3BV17
ENST00000333503.8
ENST00000562001.1