PGAP3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PGAP3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PGAP3 at tissue level.

III. Associated gene sets

GO_0006505Biological processGPI anchor metabolic process
GO_0006506Biological processGPI anchor biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding
GO_0016788Molecular functionhydrolase activity, acting on ester bonds

IV. Literature review

[source]
Gene namePGAP3
Protein namePost-GPI attachment to proteins phospholipase 3
Post-GPI attachment to proteins factor 3 (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1)
Post-GPI attachment to proteins factor 3
SynonymsUNQ546/PRO1100
CAB2
PERLD1
DescriptionFUNCTION: Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. .

FUNCTION: Involved in the lipid remodeling steps of GPI-anchor maturation. .

FUNCTION: Involved in the lipid remodeling steps of GPI-anchor maturation. .

FUNCTION: Involved in the lipid remodeling steps of GPI-anchor maturation. .

AccessionsJ3KTJ2
J3QKU0
ENST00000619169.4
ENST00000429199.6 [Q96FM1-3]
ENST00000378011.8 [Q96FM1-2]
J3QRN7
ENST00000584856.1
ENST00000300658.9 [Q96FM1-1]
ENST00000584620.5
ENST00000577337.5
Q96FM1
ENST00000579146.5
A0A087WTP0
J3QQL0