PGAM2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PGAM2 at tissue level.

III. Associated gene sets

GO_0006941Biological processstriated muscle contraction
GO_0061621Biological processcanonical glycolysis
GO_0007283Biological processspermatogenesis
GO_0007219Biological processNotch signaling pathway
GO_0006094Biological processgluconeogenesis
GO_0006096Biological processglycolytic process
GO_0046689Biological processresponse to mercury ion
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0046538Molecular function2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
GO_0016787Molecular functionhydrolase activity
GO_0004619Molecular functionphosphoglycerate mutase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0004082Molecular functionbisphosphoglycerate mutase activity

IV. Literature review

[source]
Gene namePGAM2
Protein namePhosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M)
Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4)
SynonymsPGAMM
tcag7.794
DescriptionFUNCTION: Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity.

AccessionsP15259
ENST00000297283.4
A4D2J6