Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 5 studies | 26% ± 8% | |
| cardiac muscle cell | 5 studies | 18% ± 1% | |
| retinal ganglion cell | 4 studies | 62% ± 28% | |
| retina horizontal cell | 4 studies | 32% ± 13% | |
| GABAergic neuron | 4 studies | 36% ± 10% | |
| glutamatergic neuron | 4 studies | 39% ± 13% | |
| Mueller cell | 3 studies | 24% ± 3% | |
| oligodendrocyte precursor cell | 3 studies | 23% ± 7% | |
| interneuron | 3 studies | 32% ± 13% | |
| neuron | 3 studies | 28% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 10026.01 | 258 / 258 | 98% | 74.77 | 226 / 230 |
| brain | 98% | 9130.08 | 2586 / 2642 | 100% | 98.50 | 705 / 705 |
| kidney | 100% | 4669.43 | 89 / 89 | 97% | 42.12 | 873 / 901 |
| thymus | 100% | 4384.76 | 651 / 653 | 97% | 27.56 | 585 / 605 |
| ovary | 100% | 9143.04 | 180 / 180 | 96% | 26.14 | 411 / 430 |
| skin | 96% | 3889.60 | 1731 / 1809 | 99% | 74.66 | 468 / 472 |
| prostate | 98% | 4123.99 | 240 / 245 | 95% | 27.46 | 478 / 502 |
| intestine | 98% | 5564.69 | 945 / 966 | 94% | 26.96 | 498 / 527 |
| bladder | 100% | 5658.95 | 21 / 21 | 92% | 23.71 | 462 / 504 |
| lung | 96% | 3109.46 | 555 / 578 | 94% | 23.95 | 1085 / 1155 |
| uterus | 100% | 6801.94 | 170 / 170 | 89% | 25.94 | 410 / 459 |
| esophagus | 98% | 5445.08 | 1409 / 1445 | 92% | 21.69 | 168 / 183 |
| breast | 93% | 2900.17 | 427 / 459 | 90% | 22.87 | 1008 / 1118 |
| stomach | 88% | 3582.23 | 315 / 359 | 91% | 23.21 | 260 / 286 |
| pancreas | 9% | 192.27 | 31 / 328 | 96% | 22.90 | 170 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 70.06 | 80 / 80 |
| muscle | 100% | 95756.41 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.67 | 1 / 1 |
| blood vessel | 100% | 5410.08 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 99% | 2976.01 | 238 / 241 | 0% | 0 | 0 / 0 |
| heart | 97% | 22255.91 | 832 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 19.58 | 28 / 29 |
| adipose | 93% | 3125.25 | 1116 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 23.97 | 41 / 45 |
| liver | 2% | 37.12 | 4 / 226 | 26% | 5.71 | 107 / 406 |
| peripheral blood | 20% | 1770.58 | 186 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046835 | Biological process | carbohydrate phosphorylation |
| GO_0046716 | Biological process | muscle cell cellular homeostasis |
| GO_0006096 | Biological process | glycolytic process |
| GO_0005980 | Biological process | glycogen catabolic process |
| GO_0006002 | Biological process | fructose 6-phosphate metabolic process |
| GO_0093001 | Biological process | glycolysis from storage polysaccharide through glucose-1-phosphate |
| GO_0032024 | Biological process | positive regulation of insulin secretion |
| GO_0061621 | Biological process | canonical glycolysis |
| GO_0030388 | Biological process | fructose 1,6-bisphosphate metabolic process |
| GO_0061615 | Biological process | glycolytic process through fructose-6-phosphate |
| GO_0042593 | Biological process | glucose homeostasis |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005945 | Cellular component | 6-phosphofructokinase complex |
| GO_0016020 | Cellular component | membrane |
| GO_0097228 | Cellular component | sperm principal piece |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0019900 | Molecular function | kinase binding |
| GO_0048029 | Molecular function | monosaccharide binding |
| GO_0003872 | Molecular function | 6-phosphofructokinase activity |
| GO_0016208 | Molecular function | AMP binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0070061 | Molecular function | fructose binding |
| GO_0070095 | Molecular function | fructose-6-phosphate binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PFKM |
| Protein name | PFKM protein (Phosphofructokinase (EC 2.7.1.11)) 6-phosphofructokinase type A (Phosphofructo-1-kinase isozyme A) Phosphofructokinase muscle isoform 4 Phosphofructokinase Phosphofructokinase, muscle ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase) ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase) |
| Synonyms | PFKX hCG_27714 |
| Description | FUNCTION: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. FUNCTION: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. . FUNCTION: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. . |
| Accessions | F8VW30 ENST00000547587.5 [P08237-1] ENST00000550924.6 [P08237-1] P78457 F8VVE3 ENST00000359794.11 [P08237-1] ENST00000549366.5 ENST00000546465.1 ENST00000550257.7 ENST00000642730.1 A0A0S2Z4A8 A0A2R8Y891 ENST00000629846.2 ENST00000312352.11 [P08237-1] F8VSF7 F8VNZ1 ENST00000551339.6 [P08237-1] F8VZI0 P08237 ENST00000551485.5 F8VX13 ENST00000549022.5 ENST00000552989.5 F8VTQ3 ENST00000550345.6 [P08237-1] F8VYK8 ENST00000551804.5 [P08237-2] A0A0S2Z4I1 F8VUB8 F8VZ53 F8VTT5 ENST00000340802.12 [P08237-3] H0YHB8 ENST00000548288.5 Q96I60 ENST00000547066.5 ENST00000548345.5 ENST00000549941.7 Q7KYX9 ENST00000552792.5 F8VZQ1 F8VP00 A0A0S2Z4A1 ENST00000547581.5 A0A024R0Y5 F8VSF5 ENST00000546755.5 ENST00000552752.5 ENST00000549003.5 |
