PFKFB4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PFKFB4 at single-cell level.

II. Expression across tissues

III. Associated gene sets

GO_0006000Biological processfructose metabolic process
GO_0046835Biological processcarbohydrate phosphorylation
GO_0006003Biological processfructose 2,6-bisphosphate metabolic process
GO_0005829Cellular componentcytosol
GO_0004331Molecular functionfructose-2,6-bisphosphate 2-phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0003873Molecular function6-phosphofructo-2-kinase activity

IV. Literature review

[source]
Gene namePFKFB4
Protein name6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 isoform 1 (EC 2.7.1.105, EC 3.1.3.46) (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Synonyms
DescriptionFUNCTION: Synthesis and degradation of fructose 2,6-bisphosphate.

AccessionsENST00000452531.5
ENST00000416568.5
F8WC12
C9JJ23
F8WDY1
Q66S35
ENST00000417753.5
ENST00000445633.5
Q16877
ENST00000422701.1
C9K0D8
C9JX77
ENST00000232375.8 [Q16877-1]
ENST00000383734.6 [Q16877-2]
ENST00000412035.5