PEX7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006625Biological processprotein targeting to peroxisome
GO_0008611Biological processether lipid biosynthetic process
GO_0006635Biological processfatty acid beta-oxidation
GO_0016558Biological processprotein import into peroxisome matrix
GO_0001764Biological processneuron migration
GO_0001958Biological processendochondral ossification
GO_0007031Biological processperoxisome organization
GO_0005778Cellular componentperoxisomal membrane
GO_0005829Cellular componentcytosol
GO_0005777Cellular componentperoxisome
GO_0005782Cellular componentperoxisomal matrix
GO_0019899Molecular functionenzyme binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0005053Molecular functionperoxisome matrix targeting signal-2 binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePEX7
Protein namePeroxisomal biogenesis factor 7
Peroxin-7
Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7)
SynonymshCG_1640802
PTS2R
DescriptionFUNCTION: Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal . Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol . Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex . .

AccessionsENST00000541292.6 [O00628-2]
A0A7I2V2W7
ENST00000679286.1
A0A7I2YQJ4
O00628
ENST00000678593.1
ENST00000678002.1
ENST00000367756.8
Q6FGN1
A0A7I2V2J8
ENST00000678557.1
ENST00000318471.5 [O00628-1]
A0A7I2V3V6
Q5TDQ5