Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 9 studies | 37% ± 19% | |
| epithelial cell | 4 studies | 35% ± 13% | |
| squamous epithelial cell | 3 studies | 40% ± 19% | |
| non-classical monocyte | 3 studies | 25% ± 8% | |
| neuron | 3 studies | 31% ± 11% | |
| endothelial cell | 3 studies | 24% ± 8% | |
| GABAergic neuron | 3 studies | 30% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 31% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1465.05 | 1445 / 1445 | 100% | 38.12 | 183 / 183 |
| intestine | 100% | 1199.50 | 966 / 966 | 98% | 22.96 | 516 / 527 |
| adrenal gland | 100% | 6553.18 | 258 / 258 | 98% | 37.27 | 225 / 230 |
| breast | 100% | 1424.35 | 458 / 459 | 98% | 30.87 | 1093 / 1118 |
| lung | 98% | 1335.06 | 569 / 578 | 99% | 31.22 | 1141 / 1155 |
| uterus | 100% | 1400.74 | 170 / 170 | 97% | 26.12 | 444 / 459 |
| thymus | 100% | 1764.23 | 653 / 653 | 97% | 29.42 | 585 / 605 |
| prostate | 99% | 1036.87 | 243 / 245 | 97% | 21.38 | 488 / 502 |
| brain | 97% | 3413.15 | 2571 / 2642 | 99% | 24.13 | 696 / 705 |
| kidney | 100% | 1100.96 | 89 / 89 | 96% | 23.35 | 862 / 901 |
| ovary | 100% | 1952.34 | 180 / 180 | 95% | 18.31 | 410 / 430 |
| stomach | 97% | 993.67 | 348 / 359 | 98% | 26.05 | 280 / 286 |
| bladder | 100% | 1484.81 | 21 / 21 | 93% | 21.39 | 469 / 504 |
| skin | 95% | 1421.36 | 1722 / 1809 | 96% | 37.28 | 455 / 472 |
| pancreas | 90% | 835.77 | 295 / 328 | 96% | 22.55 | 171 / 178 |
| spleen | 100% | 1266.54 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 29.82 | 45 / 45 |
| adipose | 100% | 1360.92 | 1198 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1680.91 | 1324 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 2913.75 | 848 / 861 | 0% | 0 | 0 / 0 |
| muscle | 85% | 1384.76 | 681 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 8.58 | 20 / 29 |
| eye | 0% | 0 | 0 / 0 | 45% | 5.64 | 36 / 80 |
| peripheral blood | 35% | 282.33 | 327 / 929 | 0% | 0 | 0 / 0 |
| liver | 13% | 66.96 | 29 / 226 | 22% | 4.53 | 88 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035970 | Biological process | peptidyl-threonine dephosphorylation |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0045253 | Cellular component | pyruvate dehydrogenase (lipoamide) phosphatase complex |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004741 | Molecular function | [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity |
| GO_0019909 | Molecular function | [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
| Gene name | PDP1 |
| Protein name | Pyruvate dehydrogenase phosphatase catalytic subunit 1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1) |
| Synonyms | PDP PPM2C |
| Description | FUNCTION: Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA. . |
| Accessions | E5RIV4 ENST00000521144.1 Q9P0J1 ENST00000520728.5 [Q9P0J1-1] E5RFL8 ENST00000518107.5 ENST00000518827.1 ENST00000297598.5 [Q9P0J1-1] ENST00000520614.1 ENST00000517764.1 [Q9P0J1-1] E5RI96 E5RHB9 ENST00000396200.3 [Q9P0J1-2] ENST00000518573.1 E5RIE5 |
