PDE8B | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	13 studies	47% ± 25%	Explore
pericyte	12 studies	36% ± 24%	Explore
astrocyte	10 studies	32% ± 16%	Explore
GABAergic neuron	8 studies	50% ± 27%	Explore
glutamatergic neuron	7 studies	54% ± 20%	Explore
adipocyte	7 studies	39% ± 14%	Explore
endothelial cell	6 studies	37% ± 8%	Explore
retina horizontal cell	5 studies	28% ± 10%	Explore
Mueller cell	4 studies	47% ± 25%	Explore
interneuron	4 studies	60% ± 26%	Explore
retinal cone cell	3 studies	28% ± 7%	Explore
oligodendrocyte	3 studies	29% ± 16%	Explore

Name	Number of supported studies	Average coverage
brain	12 studies	33% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3284.32	2629 / 2642	99%	16.63	701 / 705
prostate	99%	3173.35	243 / 245	90%	10.01	452 / 502
thymus	100%	16293.17	651 / 653	89%	53.06	537 / 605
uterus	99%	4525.71	168 / 170	31%	2.40	140 / 459
breast	88%	2489.97	405 / 459	34%	1.80	375 / 1118
adrenal gland	29%	244.44	75 / 258	83%	8.62	190 / 230
kidney	69%	935.64	61 / 89	34%	1.23	306 / 901
lung	89%	1028.31	516 / 578	10%	0.34	120 / 1155
adipose	98%	3467.00	1183 / 1204	0%	0	0 / 0
pancreas	68%	565.37	224 / 328	30%	1.17	53 / 178
blood vessel	92%	2852.47	1234 / 1335	0%	0	0 / 0
bladder	62%	638.19	13 / 21	15%	0.67	76 / 504
intestine	61%	693.22	587 / 966	4%	0.12	21 / 527
ovary	57%	643.75	103 / 180	5%	0.14	21 / 430
heart	57%	1661.64	494 / 861	0%	0	0 / 0
stomach	49%	794.19	175 / 359	6%	0.20	16 / 286
skin	18%	139.02	327 / 1809	5%	0.22	25 / 472
esophagus	16%	144.65	237 / 1445	4%	0.10	8 / 183
liver	8%	67.18	17 / 226	6%	0.20	25 / 406
tonsil	0%	0	0 / 0	11%	0.32	5 / 45
lymph node	0%	0	0 / 0	10%	0.37	3 / 29
spleen	2%	16.35	5 / 241	0%	0	0 / 0
muscle	1%	8.66	11 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.05	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001662	Biological process	behavioral fear response
GO_0090032	Biological process	negative regulation of steroid hormone biosynthetic process
GO_0035106	Biological process	operant conditioning
GO_0019933	Biological process	cAMP-mediated signaling
GO_0050885	Biological process	neuromuscular process controlling balance
GO_0061179	Biological process	negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO_0006198	Biological process	cAMP catabolic process
GO_0070374	Biological process	positive regulation of ERK1 and ERK2 cascade
GO_0008542	Biological process	visual learning
GO_0005575	Cellular component	cellular_component
GO_0005829	Cellular component	cytosol
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005634	Cellular component	nucleus
GO_0047555	Molecular function	3',5'-cyclic-GMP phosphodiesterase activity
GO_0004115	Molecular function	3',5'-cyclic-AMP phosphodiesterase activity
GO_0046872	Molecular function	metal ion binding

Gene name	PDE8B
Protein name	Phosphodiesterase 8B High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Phosphodiesterase (EC 3.1.4.-) PDE8B protein
Synonyms	hCG_38088 PIG22
Description	FUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland.
Accessions	Q3ZCW6 A0A2R8Y4E6 ENST00000502945.1 ENST00000505926.5 ENST00000342343.8 [O95263-4] D6RJD7 Q3ZCR2 ENST00000264917.10 [O95263-1] ENST00000505283.1 [O95263-5] O95263 ENST00000333194.8 [O95263-3] ENST00000340978.7 [O95263-6] D6RH10 D6R9W0 ENST00000646262.1 ENST00000503963.1 ENST00000346042.7 [O95263-2]

PDE8B report