PDE6A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0019933Biological processcAMP-mediated signaling
GO_0060041Biological processretina development in camera-type eye
GO_0042622Cellular componentphotoreceptor outer segment membrane
GO_0097381Cellular componentphotoreceptor disc membrane
GO_0005886Cellular componentplasma membrane
GO_0047555Molecular function3',5'-cyclic-GMP phosphodiesterase activity
GO_0004115Molecular function3',5'-cyclic-AMP phosphodiesterase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePDE6A
Protein nameRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (GMP-PDE alpha) (EC 3.1.4.35) (PDE V-B1)
Phosphodiesterase (EC 3.1.4.-)
Rod photoreceptor cGMP phosphodiesterase alpha subunit
SynonymsPDEA
DescriptionFUNCTION: Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP . This protein participates in processes of transmission and amplification of the visual signal. .

AccessionsO75316
ENST00000255266.10
ENST00000613228.1
P16499
F1T0K3