Name | Number of supported studies | Average coverage | |
---|---|---|---|
retinal rod cell | 8 studies | 92% ± 7% | |
amacrine cell | 3 studies | 26% ± 8% | |
retinal bipolar neuron | 3 studies | 23% ± 3% | |
retinal cone cell | 3 studies | 24% ± 7% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
eye | 7 studies | 52% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 96% | 220.54 | 248 / 258 | 20% | 0.87 | 45 / 230 |
ovary | 82% | 37.56 | 148 / 180 | 10% | 0.23 | 43 / 430 |
lung | 82% | 36.70 | 474 / 578 | 4% | 0.07 | 42 / 1155 |
prostate | 73% | 23.06 | 178 / 245 | 4% | 0.05 | 18 / 502 |
intestine | 56% | 153.60 | 544 / 966 | 7% | 0.17 | 39 / 527 |
muscle | 52% | 20.90 | 421 / 803 | 0% | 0 | 0 / 0 |
esophagus | 43% | 114.31 | 628 / 1445 | 6% | 0.15 | 11 / 183 |
skin | 46% | 98.27 | 840 / 1809 | 2% | 0.04 | 8 / 472 |
breast | 43% | 12.56 | 196 / 459 | 1% | 0.02 | 13 / 1118 |
adipose | 39% | 10.03 | 465 / 1204 | 0% | 0 | 0 / 0 |
brain | 35% | 9.82 | 922 / 2642 | 2% | 0.19 | 12 / 705 |
heart | 34% | 8.31 | 292 / 861 | 0% | 0 | 0 / 0 |
stomach | 17% | 3.73 | 61 / 359 | 9% | 0.21 | 26 / 286 |
bladder | 19% | 3.43 | 4 / 21 | 4% | 0.10 | 22 / 504 |
uterus | 14% | 3.40 | 23 / 170 | 5% | 0.19 | 23 / 459 |
blood vessel | 12% | 2.24 | 159 / 1335 | 0% | 0 | 0 / 0 |
spleen | 10% | 1.63 | 23 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.32 | 4 / 45 |
pancreas | 7% | 1.41 | 22 / 328 | 1% | 0.03 | 2 / 178 |
thymus | 7% | 1.54 | 45 / 653 | 0% | 0.00 | 1 / 605 |
eye | 0% | 0 | 0 / 0 | 6% | 3.64 | 5 / 80 |
kidney | 2% | 0.43 | 2 / 89 | 1% | 0.02 | 6 / 901 |
peripheral blood | 2% | 0.38 | 21 / 929 | 0% | 0 | 0 / 0 |
liver | 0% | 0.10 | 1 / 226 | 0% | 0.00 | 1 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007601 | Biological process | visual perception |
GO_0019933 | Biological process | cAMP-mediated signaling |
GO_0060041 | Biological process | retina development in camera-type eye |
GO_0042622 | Cellular component | photoreceptor outer segment membrane |
GO_0097381 | Cellular component | photoreceptor disc membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0047555 | Molecular function | 3',5'-cyclic-GMP phosphodiesterase activity |
GO_0004115 | Molecular function | 3',5'-cyclic-AMP phosphodiesterase activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | PDE6A |
Protein name | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (GMP-PDE alpha) (EC 3.1.4.35) (PDE V-B1) Phosphodiesterase (EC 3.1.4.-) Rod photoreceptor cGMP phosphodiesterase alpha subunit |
Synonyms | PDEA |
Description | FUNCTION: Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP . This protein participates in processes of transmission and amplification of the visual signal. . |
Accessions | O75316 ENST00000255266.10 ENST00000613228.1 P16499 F1T0K3 |