PCYOX1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030327Biological processprenylated protein catabolic process
GO_0030328Biological processprenylcysteine catabolic process
GO_0005764Cellular componentlysosome
GO_0070062Cellular componentextracellular exosome
GO_0034361Cellular componentvery-low-density lipoprotein particle
GO_0102149Molecular functionfarnesylcysteine lyase activity
GO_0071949Molecular functionFAD binding
GO_0001735Molecular functionprenylcysteine oxidase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePCYOX1
Protein namePrenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase)
Prenylcysteine oxidase 1 (EC 1.8.3.5)
Uncharacterized protein PCYOX1
SynonymsUNQ597/PRO1183
KIAA0908
PCL1
DescriptionFUNCTION: Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine . Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity). Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded . .

AccessionsENST00000422380.5
Q9UHG3
C9K055
ENST00000451279.1
ENST00000414812.5
C9JGT6
Q584P1
ENST00000433351.7 [Q9UHG3-1]
Q53ST0
ENST00000264441.9
F8W8W4
C9JM55