PCK2 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	6 studies	40% ± 12%	Explore
epithelial cell of proximal tubule	4 studies	27% ± 4%	Explore
epithelial cell	4 studies	29% ± 13%	Explore
hepatocyte	4 studies	33% ± 10%	Explore
conventional dendritic cell	3 studies	18% ± 1%	Explore

Name	Number of supported studies	Average coverage
intestine	4 studies	20% ± 5%	Explore
liver	3 studies	18% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	1956.20	328 / 328	100%	33.30	178 / 178
liver	100%	18898.91	226 / 226	100%	239.07	404 / 406
thymus	100%	2202.28	653 / 653	99%	43.81	601 / 605
bladder	100%	1135.19	21 / 21	98%	57.58	496 / 504
breast	100%	2261.86	458 / 459	98%	53.53	1101 / 1118
stomach	98%	1258.46	353 / 359	99%	51.56	282 / 286
prostate	100%	1003.49	244 / 245	97%	23.60	488 / 502
lung	99%	1930.10	570 / 578	97%	34.00	1125 / 1155
skin	100%	2069.39	1805 / 1809	96%	32.10	454 / 472
kidney	100%	6255.08	89 / 89	95%	35.33	858 / 901
esophagus	97%	1274.20	1405 / 1445	95%	26.03	173 / 183
intestine	89%	4764.57	856 / 966	99%	73.16	520 / 527
uterus	86%	646.74	147 / 170	97%	35.88	443 / 459
adrenal gland	97%	1083.10	249 / 258	83%	26.95	191 / 230
ovary	27%	165.68	48 / 180	88%	19.06	380 / 430
brain	54%	310.40	1428 / 2642	56%	9.00	396 / 705
lymph node	0%	0	0 / 0	100%	52.96	29 / 29
spleen	100%	2335.76	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	32.46	1 / 1
adipose	100%	2655.48	1203 / 1204	0%	0	0 / 0
blood vessel	99%	1220.50	1319 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	41.22	44 / 45
eye	0%	0	0 / 0	95%	22.38	76 / 80
peripheral blood	91%	1822.67	842 / 929	0%	0	0 / 0
heart	35%	209.53	303 / 861	0%	0	0 / 0
muscle	7%	36.12	53 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0071333	Biological process	cellular response to glucose stimulus
GO_0046327	Biological process	glycerol biosynthetic process from pyruvate
GO_0071549	Biological process	cellular response to dexamethasone stimulus
GO_0032869	Biological process	cellular response to insulin stimulus
GO_0006107	Biological process	oxaloacetate metabolic process
GO_0032024	Biological process	positive regulation of insulin secretion
GO_0042594	Biological process	response to starvation
GO_0006116	Biological process	NADH oxidation
GO_0071356	Biological process	cellular response to tumor necrosis factor
GO_0006094	Biological process	gluconeogenesis
GO_0070365	Biological process	hepatocyte differentiation
GO_0032496	Biological process	response to lipopolysaccharide
GO_0019543	Biological process	propionate catabolic process
GO_0005739	Cellular component	mitochondrion
GO_0005759	Cellular component	mitochondrial matrix
GO_0004611	Molecular function	phosphoenolpyruvate carboxykinase activity
GO_0004613	Molecular function	phosphoenolpyruvate carboxykinase (GTP) activity
GO_0030145	Molecular function	manganese ion binding
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding

Gene name	PCK2
Protein name	Phosphoenolpyruvate carboxykinase 2, mitochondrial Phosphoenolpyruvate carboxykinase 2 isoform 3 phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) (Phosphoenolpyruvate carboxykinase 2, mitochondrial) (mtPCK2)
Synonyms	hCG_40169 PEPCK2
Description	FUNCTION: Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle . Can play an active role in glyceroneogenesis and gluconeogenesis . .
Accessions	ENST00000644679.1 [Q16822-3] H0YMU6 H0YKC4 H0YMA5 ENST00000216780.9 [Q16822-1] H0YML5 ENST00000558096.5 ENST00000645217.2 [Q16822-1] Q16822 ENST00000559584.5 ENST00000545054.6 [Q16822-3] ENST00000396973.8 [Q16822-2] A0A0S2Z451 Q6IB91 ENST00000560736.5 H0YNG4 H0YMY3 A0A0S2Z4C0 ENST00000559171.1 ENST00000560106.5 ENST00000645536.1 [Q16822-3] ENST00000559837.5 A0A384MTT2 A0A0S2Z430 H0YNH9 ENST00000561286.5 [Q16822-3] ENST00000559250.5 ENST00000559503.1 H0YM31 ENST00000645709.1 [Q16822-2]

PCK2 report