PARD6A | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PARD6A at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1507.20	2635 / 2642	100%	37.17	702 / 705
pancreas	100%	850.71	328 / 328	97%	16.14	172 / 178
adrenal gland	100%	414.74	257 / 258	88%	42.79	203 / 230
kidney	93%	354.29	83 / 89	91%	12.66	822 / 901
intestine	86%	304.57	835 / 966	95%	16.33	503 / 527
stomach	87%	257.36	313 / 359	91%	13.35	261 / 286
prostate	76%	190.40	187 / 245	99%	16.14	496 / 502
breast	62%	132.43	283 / 459	92%	13.66	1028 / 1118
lung	67%	157.33	388 / 578	85%	10.38	980 / 1155
uterus	59%	131.62	101 / 170	85%	12.89	391 / 459
bladder	52%	172.19	11 / 21	88%	15.29	442 / 504
ovary	64%	173.93	116 / 180	72%	7.18	311 / 430
liver	64%	149.58	144 / 226	70%	7.23	286 / 406
thymus	52%	105.30	340 / 653	81%	7.59	490 / 605
esophagus	68%	262.56	988 / 1445	56%	5.45	102 / 183
lymph node	0%	0	0 / 0	100%	27.77	29 / 29
ureter	0%	0	0 / 0	100%	52.83	1 / 1
spleen	96%	271.34	232 / 241	0%	0	0 / 0
blood vessel	91%	275.45	1211 / 1335	0%	0	0 / 0
skin	13%	23.70	231 / 1809	76%	8.71	359 / 472
muscle	86%	265.88	691 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	7.64	37 / 45
adipose	62%	135.79	749 / 1204	0%	0	0 / 0
peripheral blood	61%	169.46	565 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	49%	3.55	39 / 80
heart	34%	64.00	289 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007163	Biological process	establishment or maintenance of cell polarity
GO_0051301	Biological process	cell division
GO_0060341	Biological process	regulation of cellular localization
GO_0007098	Biological process	centrosome cycle
GO_0050714	Biological process	positive regulation of protein secretion
GO_0001933	Biological process	negative regulation of protein phosphorylation
GO_1904781	Biological process	positive regulation of protein localization to centrosome
GO_0016032	Biological process	viral process
GO_0045197	Biological process	establishment or maintenance of epithelial cell apical/basal polarity
GO_0045217	Biological process	cell-cell junction maintenance
GO_0001726	Cellular component	ruffle
GO_0016324	Cellular component	apical plasma membrane
GO_0070160	Cellular component	tight junction
GO_0005886	Cellular component	plasma membrane
GO_0034451	Cellular component	centriolar satellite
GO_0005813	Cellular component	centrosome
GO_0005829	Cellular component	cytosol
GO_0005938	Cellular component	cell cortex
GO_0120157	Cellular component	PAR polarity complex
GO_0005923	Cellular component	bicellular tight junction
GO_0005634	Cellular component	nucleus
GO_0030742	Molecular function	GTP-dependent protein binding
GO_0031267	Molecular function	small GTPase binding
GO_0005515	Molecular function	protein binding

Gene name	PARD6A
Protein name	Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40) Par-6 family cell polarity regulator alpha
Synonyms	PAR6A
Description	FUNCTION: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins . Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization . .
Accessions	ENST00000458121.7 [Q9NPB6-2] ENST00000602551.5 Q9NPB6 R4GMM2 ENST00000219255.3 [Q9NPB6-1]

PARD6A report