PAQR8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048545Biological processresponse to steroid hormone
GO_0048477Biological processoogenesis
GO_0043401Biological processsteroid hormone receptor signaling pathway
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_0005496Molecular functionsteroid binding
GO_0003707Molecular functionnuclear steroid receptor activity

IV. Literature review

[source]
Gene namePAQR8
Protein nameMembrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)
Alternative protein PAQR8
Progestin and adipoQ receptor family member 8
SynonymsLMPB1
MPRB
C6orf33
DescriptionFUNCTION: Plasma membrane progesterone (P4) receptor coupled to G proteins . Seems to act through a G(i) mediated pathway . May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone . .

AccessionsD6RCM7
ENST00000360726.3
Q8TEZ7
L8EBD2
ENST00000512121.1
ENST00000442253.3