I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 21% ± 5% | |
| ciliated cell | 3 studies | 26% ± 2% | |
| basal cell | 3 studies | 21% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 21% ± 5% | |
| ciliated cell | 3 studies | 26% ± 2% | |
| basal cell | 3 studies | 21% ± 6% |
Insufficient scRNA-seq data for expression of PAQR7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| uterus | 100% | 1493.16 | 170 / 170 | 100% | 28.57 | 457 / 459 |
| thymus | 100% | 655.33 | 651 / 653 | 99% | 26.32 | 600 / 605 |
| kidney | 100% | 2082.38 | 89 / 89 | 99% | 26.89 | 890 / 901 |
| skin | 100% | 2202.13 | 1809 / 1809 | 98% | 19.37 | 462 / 472 |
| bladder | 100% | 1639.19 | 21 / 21 | 97% | 42.13 | 489 / 504 |
| prostate | 100% | 1039.92 | 244 / 245 | 97% | 12.49 | 488 / 502 |
| ovary | 100% | 3400.47 | 180 / 180 | 97% | 14.72 | 415 / 430 |
| brain | 98% | 645.37 | 2576 / 2642 | 99% | 15.83 | 695 / 705 |
| adrenal gland | 100% | 2779.21 | 258 / 258 | 95% | 14.43 | 219 / 230 |
| breast | 97% | 631.80 | 445 / 459 | 98% | 15.53 | 1096 / 1118 |
| lung | 98% | 699.33 | 566 / 578 | 96% | 18.61 | 1112 / 1155 |
| esophagus | 100% | 1104.91 | 1443 / 1445 | 92% | 10.27 | 168 / 183 |
| intestine | 99% | 702.11 | 958 / 966 | 91% | 9.54 | 481 / 527 |
| pancreas | 90% | 395.19 | 294 / 328 | 100% | 21.18 | 178 / 178 |
| stomach | 100% | 743.81 | 359 / 359 | 83% | 8.40 | 236 / 286 |
| liver | 63% | 262.78 | 142 / 226 | 79% | 8.56 | 319 / 406 |
| spleen | 100% | 1261.27 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.48 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 58.15 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 15.91 | 79 / 80 |
| blood vessel | 99% | 632.56 | 1315 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 97% | 589.71 | 1170 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 8.75 | 24 / 29 |
| peripheral blood | 55% | 320.54 | 515 / 929 | 0% | 0 | 0 / 0 |
| heart | 47% | 156.80 | 402 / 861 | 0% | 0 | 0 / 0 |
| muscle | 20% | 56.06 | 157 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0048545 | Biological process | response to steroid hormone |
| GO_0048477 | Biological process | oogenesis |
| GO_0043401 | Biological process | steroid hormone receptor signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0005496 | Molecular function | steroid binding |
| GO_0003707 | Molecular function | nuclear steroid receptor activity |
| Gene name | PAQR7 |
| Protein name | Membrane progestin receptor alpha (mPR alpha) (Membrane progesterone P4 receptor alpha) (Membrane progesterone receptor alpha) (Progesterone and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member VII) PAQR7 protein |
| Synonyms | MRPA |
| Description | FUNCTION: Plasma membrane progesterone (P4) receptor coupled to G proteins . Seems to act through a G(i) mediated pathway . May be involved in oocyte maturation . Involved in neurosteroid inhibition of apoptosis . Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone . . |
| Accessions | Q86WK9 A1L182 ENST00000374296.4 ENST00000675840.1 |
