PAQR6 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	5 studies	26% ± 8%	Explore
astrocyte	4 studies	23% ± 9%	Explore

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PAQR6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	41966.82	2638 / 2642	100%	233.67	703 / 705
ureter	0%	0	0 / 0	100%	9.12	1 / 1
prostate	8%	142.09	19 / 245	91%	17.08	457 / 502
pancreas	0%	0	0 / 328	81%	6.54	145 / 178
adrenal gland	0%	0	0 / 258	78%	14.02	180 / 230
thymus	0%	7.43	1 / 653	78%	6.22	472 / 605
breast	1%	11.83	3 / 459	77%	9.81	856 / 1118
lymph node	0%	0	0 / 0	76%	6.00	22 / 29
uterus	0%	0	0 / 170	70%	6.22	320 / 459
bladder	0%	0	0 / 21	65%	6.65	326 / 504
skin	14%	276.12	247 / 1809	50%	4.61	234 / 472
ovary	1%	30.71	1 / 180	61%	5.12	262 / 430
esophagus	1%	11.84	8 / 1445	55%	5.16	101 / 183
intestine	6%	140.24	61 / 966	47%	3.18	250 / 527
kidney	1%	18.49	1 / 89	50%	4.11	448 / 901
lung	0%	0	0 / 578	46%	3.79	532 / 1155
stomach	1%	13.32	3 / 359	43%	2.48	122 / 286
tonsil	0%	0	0 / 0	42%	2.44	19 / 45
eye	0%	0	0 / 0	39%	2.43	31 / 80
liver	0%	8.26	1 / 226	33%	2.99	133 / 406
peripheral blood	14%	364.49	127 / 929	0%	0	0 / 0
spleen	1%	18.65	2 / 241	0%	0	0 / 0
adipose	0%	6.23	4 / 1204	0%	0	0 / 0
muscle	0%	2.38	1 / 803	0%	0	0 / 0
heart	0%	6.66	1 / 861	0%	0	0 / 0
blood vessel	0%	1.18	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	PAQR6
Protein name	Progestin and adipoQ receptor family member 6 (cDNA FLJ53340, highly similar to Homo sapiens progestin and adipoQ receptor family member VI (PAQR6), transcript variant 1, mRNA) Membrane progestin receptor delta (mPR delta) (Membrane progesterone P4 receptor delta) (Membrane progesterone receptor delta) (Progesterone and adipoQ receptor family member 6) (Progestin and adipoQ receptor family member 6) Progestin and adipoQ receptor family member VI variant 3 Progestin and adipoQ receptor family member VI variant 4 Progestin and adipoQ receptor family member VI variant 5 Progestin and adipoQ receptor family member VI, isoform CRA_a (cDNA FLJ54068, highly similar to Progestin and adipoQ receptor family member 6) PAQR6 protein Progestin and adipoQ receptor family member VI, isoform CRA_f (cDNA FLJ52547, highly similar to Progestin and adipoQ receptor family member 6) Progestin and adipoQ receptor family member 6 Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI, isoform CRA_e)
Synonyms	hCG_17185
Description	FUNCTION: Plasma membrane progesterone (P4) receptor coupled to G proteins . Seems to act through a G(s) mediated pathway . Involved in neurosteroid inhibition of apoptosis . May be involved in regulating rapid P4 signaling in the nervous system . Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone . .
Accessions	Q6IQ11 ENST00000340183.10 ENST00000368270.2 [Q6TCH4-4] K9J961 ENST00000652405.1 K9J969 Q5TCK7 ENST00000470198.5 B4DJ42 Q7Z4Q8 K9J974 ENST00000356983.7 [Q6TCH4-5] ENST00000623241.3 A0A494C0R3 Q6TCH4 Q5TCK8 ENST00000335852.6 [Q6TCH4-2] ENST00000292291.10 [Q6TCH4-1] ENST00000613336.4 Q5TCK5 ENST00000612424.4 ENST00000540423.5 A0A494C1I0

GO_0005886	Cellular component	plasma membrane
GO_0005496	Molecular function	steroid binding
GO_0038023	Molecular function	signaling receptor activity
GO_0005515	Molecular function	protein binding

PAQR6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review