Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 16 studies | 29% ± 13% | |
fibroblast | 14 studies | 26% ± 8% | |
type I pneumocyte | 11 studies | 44% ± 16% | |
non-classical monocyte | 11 studies | 23% ± 5% | |
macrophage | 11 studies | 27% ± 8% | |
pericyte | 9 studies | 23% ± 6% | |
capillary endothelial cell | 9 studies | 32% ± 8% | |
endothelial cell of artery | 6 studies | 36% ± 6% | |
pancreatic A cell | 4 studies | 52% ± 28% | |
myeloid cell | 4 studies | 23% ± 7% | |
mesothelial cell | 4 studies | 24% ± 6% | |
epithelial cell | 4 studies | 29% ± 8% | |
type B pancreatic cell | 3 studies | 64% ± 24% | |
dendritic cell | 3 studies | 21% ± 7% | |
adipocyte | 3 studies | 20% ± 1% | |
hepatocyte | 3 studies | 64% ± 15% | |
GABAergic neuron | 3 studies | 25% ± 3% | |
enterocyte | 3 studies | 24% ± 5% | |
monocyte | 3 studies | 26% ± 7% | |
brush cell | 3 studies | 33% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 2875.02 | 327 / 328 | 96% | 47.67 | 170 / 178 |
lung | 100% | 14417.93 | 578 / 578 | 95% | 51.01 | 1098 / 1155 |
liver | 100% | 7068.48 | 226 / 226 | 94% | 42.71 | 381 / 406 |
breast | 99% | 4234.10 | 456 / 459 | 89% | 52.84 | 995 / 1118 |
kidney | 100% | 2359.58 | 89 / 89 | 88% | 39.11 | 794 / 901 |
intestine | 86% | 4612.94 | 831 / 966 | 96% | 61.78 | 504 / 527 |
adrenal gland | 100% | 25227.03 | 258 / 258 | 69% | 87.12 | 158 / 230 |
esophagus | 79% | 1248.22 | 1142 / 1445 | 85% | 27.00 | 156 / 183 |
stomach | 63% | 786.03 | 227 / 359 | 94% | 41.88 | 268 / 286 |
bladder | 95% | 1797.10 | 20 / 21 | 60% | 25.49 | 303 / 504 |
uterus | 89% | 1800.19 | 152 / 170 | 65% | 17.08 | 298 / 459 |
ovary | 100% | 4487.46 | 180 / 180 | 43% | 7.03 | 184 / 430 |
thymus | 100% | 3463.08 | 650 / 653 | 36% | 7.24 | 217 / 605 |
prostate | 83% | 1339.80 | 203 / 245 | 47% | 8.18 | 237 / 502 |
brain | 34% | 409.55 | 903 / 2642 | 80% | 13.80 | 566 / 705 |
adipose | 100% | 5127.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
skin | 49% | 2877.78 | 886 / 1809 | 47% | 12.29 | 223 / 472 |
blood vessel | 94% | 2075.84 | 1249 / 1335 | 0% | 0 | 0 / 0 |
spleen | 85% | 1118.37 | 205 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 23.69 | 36 / 45 |
heart | 76% | 1213.75 | 652 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 72% | 11.94 | 21 / 29 |
muscle | 23% | 247.32 | 188 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 20% | 2.32 | 16 / 80 |
peripheral blood | 5% | 53.47 | 48 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050428 | Biological process | 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process |
GO_0060348 | Biological process | bone development |
GO_0007596 | Biological process | blood coagulation |
GO_0042445 | Biological process | hormone metabolic process |
GO_0000103 | Biological process | sulfate assimilation |
GO_0005829 | Cellular component | cytosol |
GO_0016779 | Molecular function | nucleotidyltransferase activity |
GO_0004781 | Molecular function | sulfate adenylyltransferase (ATP) activity |
GO_0004020 | Molecular function | adenylylsulfate kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | PAPSS2 |
Protein name | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK 2) (SK2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] 3'-phosphoadenosine 5'-phosphosulfate synthase 2, isoform CRA_b (Epididymis secretory sperm binding protein) (cDNA, FLJ92929, highly similar to Homo sapiens 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2), mRNA) |
Synonyms | hCG_23331 ATPSK2 |
Description | FUNCTION: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases . In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway . Plays indirectly an important role in skeletogenesis during postnatal growth . . |
Accessions | ENST00000456849.2 [O95340-2] O95340 ENST00000361175.8 [O95340-1] Q5TB52 |