Insufficient scRNA-seq data for expression of PADI6 at single-cell level.
Insufficient scRNA-seq data for expression of PADI6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| peripheral blood | 76% | 14.56 | 707 / 929 | 0% | 0 | 0 / 0 |
| spleen | 68% | 4.55 | 165 / 241 | 0% | 0 | 0 / 0 |
| lung | 41% | 1.50 | 236 / 578 | 1% | 0.02 | 8 / 1155 |
| muscle | 33% | 1.49 | 269 / 803 | 0% | 0 | 0 / 0 |
| ovary | 31% | 98.10 | 55 / 180 | 0% | 0 | 0 / 430 |
| kidney | 19% | 0.55 | 17 / 89 | 0% | 0.01 | 3 / 901 |
| liver | 19% | 0.56 | 43 / 226 | 0% | 0 | 0 / 406 |
| adipose | 17% | 0.52 | 200 / 1204 | 0% | 0 | 0 / 0 |
| skin | 14% | 0.81 | 258 / 1809 | 1% | 0.01 | 4 / 472 |
| bladder | 14% | 0.76 | 3 / 21 | 0% | 0 | 0 / 504 |
| brain | 13% | 0.38 | 346 / 2642 | 0% | 0 | 0 / 705 |
| breast | 11% | 0.32 | 51 / 459 | 0% | 0.00 | 2 / 1118 |
| heart | 11% | 0.28 | 91 / 861 | 0% | 0 | 0 / 0 |
| esophagus | 8% | 0.22 | 120 / 1445 | 2% | 0.27 | 4 / 183 |
| thymus | 10% | 0.30 | 67 / 653 | 0% | 0 | 0 / 605 |
| blood vessel | 10% | 0.27 | 133 / 1335 | 0% | 0 | 0 / 0 |
| uterus | 9% | 0.28 | 16 / 170 | 0% | 0.01 | 2 / 459 |
| intestine | 8% | 0.25 | 80 / 966 | 0% | 0.02 | 2 / 527 |
| adrenal gland | 6% | 0.16 | 16 / 258 | 0% | 0 | 0 / 230 |
| pancreas | 5% | 0.17 | 18 / 328 | 1% | 0.01 | 1 / 178 |
| stomach | 6% | 0.14 | 20 / 359 | 0% | 0.00 | 1 / 286 |
| prostate | 6% | 0.15 | 14 / 245 | 0% | 0 | 0 / 502 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0040016 | Biological process | embryonic cleavage |
| GO_0043143 | Biological process | regulation of translation by machinery localization |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0007028 | Biological process | cytoplasm organization |
| GO_0045111 | Cellular component | intermediate filament cytoskeleton |
| GO_0060473 | Cellular component | cortical granule |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0004668 | Molecular function | protein-arginine deiminase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PADI6 |
| Protein name | Protein-arginine deiminase type-6 (EC 3.5.3.15) (Peptidyl arginine deiminase-like protein) (Peptidylarginine deiminase VI) (hPADVI) (Protein-arginine deiminase type VI) |
| Synonyms | PAD6 |
| Description | FUNCTION: Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo . .; FUNCTION: Catalyzes the deimination of arginine residues of proteins (By similarity). In oocytes, is released during cortical reaction and plays a role in preimplantation cleavage and early embryonic development (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo . . |
| Accessions | ENST00000625380.1 Q6TGC4 ENST00000619609.1 |