OTUD6B | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	21% ± 3%	Explore
glutamatergic neuron	3 studies	31% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	23% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	721.04	1445 / 1445	100%	14.40	183 / 183
brain	100%	767.84	2640 / 2642	100%	19.66	705 / 705
ovary	100%	854.91	180 / 180	99%	10.21	425 / 430
breast	100%	862.76	459 / 459	98%	14.80	1101 / 1118
lung	100%	669.16	576 / 578	99%	12.71	1141 / 1155
uterus	100%	906.24	170 / 170	98%	12.57	450 / 459
bladder	100%	804.52	21 / 21	97%	12.86	491 / 504
prostate	100%	704.95	245 / 245	97%	10.47	486 / 502
thymus	100%	876.99	653 / 653	97%	7.94	585 / 605
pancreas	100%	413.46	327 / 328	97%	8.37	172 / 178
intestine	100%	757.49	966 / 966	95%	13.02	502 / 527
stomach	99%	532.11	357 / 359	95%	12.33	272 / 286
adrenal gland	100%	645.60	258 / 258	93%	9.23	215 / 230
skin	100%	847.26	1808 / 1809	90%	13.21	426 / 472
kidney	100%	550.45	89 / 89	88%	6.82	794 / 901
liver	97%	322.82	220 / 226	86%	6.37	348 / 406
adipose	100%	837.63	1204 / 1204	0%	0	0 / 0
blood vessel	100%	787.33	1335 / 1335	0%	0	0 / 0
muscle	100%	822.48	803 / 803	0%	0	0 / 0
spleen	100%	572.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	11.21	45 / 45
ureter	0%	0	0 / 0	100%	11.98	1 / 1
heart	98%	511.47	842 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	10.06	28 / 29
eye	0%	0	0 / 0	55%	5.97	44 / 80
peripheral blood	53%	500.09	489 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0043248	Biological process	proteasome assembly
GO_0008283	Biological process	cell population proliferation
GO_0006508	Biological process	proteolysis
GO_0016579	Biological process	protein deubiquitination
GO_0016281	Cellular component	eukaryotic translation initiation factor 4F complex
GO_0005515	Molecular function	protein binding
GO_0004843	Molecular function	cysteine-type deubiquitinase activity

Gene name	OTUD6B
Protein name	OTU deubiquitinase 6B ubiquitinyl hydrolase 1 (EC 3.4.19.12) Deubiquitinase OTUD6B (EC 3.4.19.12) (DUBA-5) (OTU domain-containing protein 6B)
Synonyms	hCG_32310 DUBA5 CGI-77
Description	FUNCTION: [Isoform 1]: Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 . May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation . May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation . May also play a role in proteasome assembly and function . .; FUNCTION: [Isoform 2]: Stimulates protein synthesis. Influences the expression of CCND1/cyclin D1 by promoting its translation and regulates MYC/c-Myc protein stability. .
Accessions	Q8N6M0 ENST00000617869.4 ENST00000522894.5 ENST00000404789.8 [Q8N6M0-1] A0A0C4DH76 A0A087X0W9 ENST00000285420.8 ENST00000615618.1 [Q8N6M0-2]

OTUD6B report