Insufficient scRNA-seq data for expression of OTOP2 at single-cell level.
Insufficient scRNA-seq data for expression of OTOP2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 55% | 568.07 | 533 / 966 | 8% | 0.26 | 40 / 527 |
| esophagus | 38% | 39.63 | 551 / 1445 | 22% | 1.09 | 41 / 183 |
| uterus | 44% | 18.75 | 75 / 170 | 7% | 0.16 | 30 / 459 |
| skin | 38% | 15.10 | 685 / 1809 | 1% | 0.01 | 3 / 472 |
| lung | 0% | 0.03 | 1 / 578 | 8% | 0.23 | 96 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.11 | 3 / 45 |
| stomach | 1% | 0.13 | 2 / 359 | 3% | 0.13 | 9 / 286 |
| bladder | 0% | 0 | 0 / 21 | 3% | 0.06 | 16 / 504 |
| prostate | 2% | 0.58 | 6 / 245 | 0% | 0 | 0 / 502 |
| breast | 2% | 6.49 | 8 / 459 | 0% | 0.01 | 4 / 1118 |
| brain | 2% | 0.34 | 50 / 2642 | 0% | 0.00 | 1 / 705 |
| adrenal gland | 0% | 0.06 | 1 / 258 | 1% | 0.01 | 2 / 230 |
| adipose | 1% | 0.24 | 15 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.07 | 4 / 929 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.09 | 3 / 803 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0.07 | 2 / 653 | 0% | 0 | 0 / 605 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0.00 | 1 / 430 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.01 | 2 / 901 |
| blood vessel | 0% | 0.02 | 2 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 0% | 0 | 0 / 178 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902600 | Biological process | proton transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0015252 | Molecular function | proton channel activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | OTOP2 |
| Protein name | Otopetrin 2 Proton channel OTOP2 (Otopetrin-2) |
| Synonyms | |
| Description | FUNCTION: Proton-selective ion channel open at neutral pH. Actives at neutral and alkaline extracellular pH, likely participates in some alkali-related physiological activities. . |
| Accessions | Q7RTS6 ENST00000331427.9 A0A6E1ZAN8 ENST00000580223.2 |