OSBPL5 | OmnibusX

Name	Number of supported studies	Average coverage
natural killer cell	13 studies	20% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	22% ± 6%	Explore
endothelial cell	6 studies	28% ± 10%	Explore
GABAergic neuron	6 studies	26% ± 13%	Explore
endothelial cell of lymphatic vessel	5 studies	27% ± 6%	Explore
glutamatergic neuron	4 studies	39% ± 13%	Explore
fibroblast	4 studies	23% ± 10%	Explore
neuron	3 studies	23% ± 4%	Explore
retina horizontal cell	3 studies	19% ± 3%	Explore
oligodendrocyte	3 studies	21% ± 3%	Explore

Name	Number of supported studies	Average coverage
brain	5 studies	29% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	5351.98	245 / 245	100%	28.12	501 / 502
breast	100%	4039.23	459 / 459	100%	21.00	1113 / 1118
thymus	100%	3252.49	651 / 653	99%	19.41	598 / 605
intestine	100%	4603.61	966 / 966	98%	18.15	519 / 527
esophagus	100%	4250.55	1444 / 1445	98%	12.89	180 / 183
skin	100%	4568.84	1809 / 1809	96%	15.09	452 / 472
lung	100%	3582.33	577 / 578	96%	12.88	1108 / 1155
bladder	100%	4775.67	21 / 21	96%	12.51	482 / 504
stomach	99%	2574.67	355 / 359	96%	16.09	274 / 286
kidney	100%	2190.99	89 / 89	95%	11.57	852 / 901
uterus	100%	5486.21	170 / 170	93%	12.21	427 / 459
ovary	100%	2759.54	180 / 180	92%	7.88	394 / 430
brain	88%	1167.78	2333 / 2642	100%	15.68	702 / 705
pancreas	92%	1144.81	301 / 328	96%	18.44	170 / 178
adrenal gland	100%	1516.33	257 / 258	74%	5.47	171 / 230
adipose	100%	3979.52	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5553.48	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	12.78	80 / 80
spleen	100%	4962.80	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.96	1 / 1
heart	98%	1607.33	847 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	87%	8.02	39 / 45
muscle	82%	1011.48	660 / 803	0%	0	0 / 0
peripheral blood	67%	1580.11	621 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	3.44	18 / 29
liver	9%	79.55	20 / 226	25%	2.33	102 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0008203	Biological process	cholesterol metabolic process
GO_0120009	Biological process	intermembrane lipid transfer
GO_0036150	Biological process	phosphatidylserine acyl-chain remodeling
GO_0015914	Biological process	phospholipid transport
GO_0006893	Biological process	Golgi to plasma membrane transport
GO_0030301	Biological process	cholesterol transport
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0140268	Cellular component	endoplasmic reticulum-plasma membrane contact site
GO_0005829	Cellular component	cytosol
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0140343	Molecular function	phosphatidylserine transfer activity
GO_0032934	Molecular function	sterol binding
GO_0070273	Molecular function	phosphatidylinositol-4-phosphate binding
GO_0001786	Molecular function	phosphatidylserine binding
GO_0015485	Molecular function	cholesterol binding
GO_0005548	Molecular function	phospholipid transporter activity
GO_0008142	Molecular function	oxysterol binding

Gene name	OSBPL5
Protein name	Oxysterol-binding protein Oxysterol-binding protein-related protein 5 (ORP-5) (OSBP-related protein 5) (Oxysterol-binding protein homolog 1) Oxysterol binding protein like 5
Synonyms	KIAA1534 OBPH1 ORP5
Description	FUNCTION: Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner . May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes . Binds 25-hydroxycholesterol and cholesterol . .
Accessions	E9PLN3 Q9H0X9 ENST00000534454.5 ENST00000263650.12 [Q9H0X9-1] ENST00000533721.5 E9PIJ6 ENST00000348039.9 [Q9H0X9-2] ENST00000525498.5 [Q9H0X9-3] ENST00000533234.5 H0YCD7 ENST00000530372.5 E9PQB4 E9PNH0 ENST00000471998.6 E9PRA9 E9PPQ2 ENST00000534157.1 E9PJE6 ENST00000389989.7 [Q9H0X9-2] ENST00000526122.5 ENST00000478260.5

OSBPL5 report