Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 32% ± 17% | |
| GABAergic neuron | 3 studies | 34% ± 4% | |
| glutamatergic neuron | 3 studies | 40% ± 5% | |
| astrocyte | 3 studies | 23% ± 6% | |
| oligodendrocyte | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 2987.62 | 258 / 258 | 100% | 24.38 | 230 / 230 |
| bladder | 100% | 1762.86 | 21 / 21 | 100% | 19.20 | 504 / 504 |
| breast | 100% | 1761.71 | 459 / 459 | 100% | 23.37 | 1118 / 1118 |
| esophagus | 100% | 1926.33 | 1445 / 1445 | 100% | 18.01 | 183 / 183 |
| kidney | 100% | 1429.39 | 89 / 89 | 100% | 14.41 | 901 / 901 |
| ovary | 100% | 1553.97 | 180 / 180 | 100% | 15.80 | 430 / 430 |
| prostate | 100% | 1691.22 | 245 / 245 | 100% | 15.61 | 502 / 502 |
| uterus | 100% | 1850.26 | 170 / 170 | 100% | 19.98 | 459 / 459 |
| skin | 100% | 2400.05 | 1808 / 1809 | 100% | 26.91 | 472 / 472 |
| thymus | 100% | 1484.74 | 652 / 653 | 100% | 18.67 | 605 / 605 |
| intestine | 100% | 1494.91 | 966 / 966 | 100% | 19.19 | 526 / 527 |
| liver | 100% | 1141.23 | 226 / 226 | 100% | 10.76 | 405 / 406 |
| stomach | 100% | 1233.20 | 358 / 359 | 100% | 18.05 | 286 / 286 |
| lung | 99% | 1531.97 | 575 / 578 | 100% | 19.42 | 1155 / 1155 |
| brain | 99% | 1456.50 | 2628 / 2642 | 100% | 24.66 | 705 / 705 |
| pancreas | 94% | 627.18 | 308 / 328 | 99% | 16.82 | 177 / 178 |
| adipose | 100% | 1815.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2294.77 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 21.27 | 29 / 29 |
| muscle | 100% | 4644.67 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1469.90 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 17.21 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.00 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 98% | 14.41 | 78 / 80 |
| heart | 97% | 1397.92 | 833 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 72% | 1058.10 | 665 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0019511 | Biological process | peptidyl-proline hydroxylation |
| GO_0008283 | Biological process | cell population proliferation |
| GO_0018126 | Biological process | protein hydroxylation |
| GO_0034063 | Biological process | stress granule assembly |
| GO_0006449 | Biological process | regulation of translational termination |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0010494 | Cellular component | cytoplasmic stress granule |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0031543 | Molecular function | peptidyl-proline dioxygenase activity |
| GO_0005506 | Molecular function | iron ion binding |
| GO_0031544 | Molecular function | peptidyl-proline 3-dioxygenase activity |
| GO_0031418 | Molecular function | L-ascorbic acid binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | OGFOD1 |
| Protein name | Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase) Alternative protein OGFOD1 2-oxoglutarate and iron dependent oxygenase domain containing 1 |
| Synonyms | TPA1 KIAA1612 |
| Description | FUNCTION: Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation. . |
| Accessions | ENST00000566157.6 [Q8N543-1] H3BP48 L8ECH8 ENST00000568397.1 H3BR02 ENST00000562150.5 H3BR79 ENST00000569802.5 H3BUA6 J3KNR5 ENST00000561646.5 A0A0A0MTR2 ENST00000565682.5 Q8N543 ENST00000336111.9 |
