NUPR2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NUPR2 at tissue level.

III. Associated gene sets

GO_0006974Biological processDNA damage response
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0045786Biological processnegative regulation of cell cycle
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0009267Biological processcellular response to starvation
GO_0051726Biological processregulation of cell cycle
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameNUPR2
Protein nameNuclear protein 2 (Nuclear transcriptional regulator 1-like protein) (Nuclear transcriptional regulator protein 2)
SynonymsNUPR1L
DescriptionFUNCTION: Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells . Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation . Plays a role as a negative regulator of the protumoral factor NUPR1 . .

AccessionsA6NF83
ENST00000329309.4