NUP85 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006913Biological processnucleocytoplasmic transport
GO_0006406Biological processmRNA export from nucleus
GO_0048246Biological processmacrophage chemotaxis
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0006606Biological processprotein import into nucleus
GO_0072006Biological processnephron development
GO_0030032Biological processlamellipodium assembly
GO_0000776Cellular componentkinetochore
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005643Cellular componentnuclear pore
GO_0031965Cellular componentnuclear membrane
GO_0031080Cellular componentnuclear pore outer ring
GO_0005819Cellular componentspindle
GO_0005635Cellular componentnuclear envelope
GO_0016020Cellular componentmembrane
GO_0017056Molecular functionstructural constituent of nuclear pore
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNUP85
Protein nameNuclear pore complex protein Nup85
Nucleoporin 85
Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1)
SynonymsPCNT1
NUP75
DescriptionFUNCTION: Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance . As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus . The Nup107-160 complex seems to be required for spindle assembly during mitosis . NUP85 is required for membrane clustering of CCL2-activated CCR2 . Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade . Involved in nephrogenesis . .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

FUNCTION: Functions as a component of the nuclear pore complex (NPC). .

AccessionsJ3KT10
J3QL54
J3KTC7
ENST00000583569.5
ENST00000580879.5
J3KS87
J3QLH0
J3QLV0
Q9BW27
ENST00000579557.5
ENST00000578830.5
ENST00000583070.5
J3QL91
J3KRC0
J3QLD4
ENST00000245544.9 [Q9BW27-1]
ENST00000584155.1
ENST00000579324.5
ENST00000579900.5
ENST00000583877.5
J3KSH3
ENST00000578987.1
F5H0W7
ENST00000540768.5
ENST00000581104.5
J3QRY3
ENST00000579298.5
J3QL49
ENST00000579838.1
J3QS63