NUF2 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	3 studies	24% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of NUF2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	94%	533.18	1695 / 1809	84%	15.82	398 / 472
lung	78%	95.81	450 / 578	86%	18.39	999 / 1155
intestine	67%	139.07	644 / 966	93%	16.30	489 / 527
stomach	60%	97.56	216 / 359	92%	16.09	263 / 286
bladder	57%	28.38	12 / 21	93%	22.28	470 / 504
esophagus	53%	188.88	765 / 1445	97%	21.80	177 / 183
ovary	47%	33.46	85 / 180	96%	15.79	411 / 430
breast	49%	33.34	225 / 459	90%	19.71	1009 / 1118
uterus	34%	22.36	58 / 170	98%	31.74	449 / 459
brain	57%	30.21	1505 / 2642	50%	7.79	350 / 705
lymph node	0%	0	0 / 0	100%	27.55	29 / 29
spleen	100%	330.37	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	26.40	45 / 45
ureter	0%	0	0 / 0	100%	7.23	1 / 1
adrenal gland	64%	55.89	165 / 258	22%	2.96	50 / 230
pancreas	12%	6.81	38 / 328	67%	7.20	119 / 178
liver	17%	19.09	38 / 226	49%	6.00	197 / 406
prostate	53%	32.29	130 / 245	9%	0.68	44 / 502
peripheral blood	53%	594.75	497 / 929	0%	0	0 / 0
thymus	35%	22.60	229 / 653	16%	4.98	94 / 605
adipose	49%	38.76	595 / 1204	0%	0	0 / 0
kidney	31%	27.99	28 / 89	10%	0.90	88 / 901
blood vessel	29%	18.66	393 / 1335	0%	0	0 / 0
heart	16%	11.21	141 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.20	3 / 80
muscle	3%	1.27	21 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0051315	Biological process	attachment of mitotic spindle microtubules to kinetochore
GO_0045132	Biological process	meiotic chromosome segregation
GO_0008608	Biological process	attachment of spindle microtubules to kinetochore
GO_0051301	Biological process	cell division
GO_0007094	Biological process	mitotic spindle assembly checkpoint signaling
GO_0051383	Biological process	kinetochore organization
GO_0007059	Biological process	chromosome segregation
GO_0007052	Biological process	mitotic spindle organization
GO_0031262	Cellular component	Ndc80 complex
GO_0000776	Cellular component	kinetochore
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0016020	Cellular component	membrane
GO_0044877	Molecular function	protein-containing complex binding
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function
GO_0008017	Molecular function	microtubule binding

Gene name	NUF2
Protein name	NUF2 component of NDC80 kinetochore complex Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1)
Synonyms	NUF2R CDCA1
Description	FUNCTION: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore . The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules . .
Accessions	ENST00000450453.6 ENST00000442820.5 B1AQT4 E9PKH1 ENST00000271452.8 E9PP32 ENST00000524800.5 ENST00000497990.1 ENST00000367900.7 Q9BZD4 ENST00000534289.5 B1AQT3 E9PQC4

NUF2 report