NUDT11 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of NUDT11 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	99%	639.74	243 / 245	98%	37.28	490 / 502
brain	96%	1445.96	2545 / 2642	100%	61.97	702 / 705
uterus	99%	407.20	168 / 170	39%	8.54	178 / 459
adrenal gland	46%	115.20	118 / 258	74%	15.43	170 / 230
ovary	100%	828.00	180 / 180	14%	1.50	59 / 430
pancreas	91%	292.83	299 / 328	21%	1.60	38 / 178
blood vessel	95%	275.70	1266 / 1335	0%	0	0 / 0
bladder	81%	204.71	17 / 21	13%	2.09	68 / 504
skin	64%	314.83	1152 / 1809	24%	3.11	113 / 472
esophagus	49%	92.68	710 / 1445	37%	6.56	68 / 183
intestine	67%	206.36	643 / 966	5%	0.38	26 / 527
breast	49%	87.93	223 / 459	22%	2.34	245 / 1118
thymus	11%	17.06	74 / 653	47%	7.10	287 / 605
tonsil	0%	0	0 / 0	58%	9.88	26 / 45
lung	6%	9.92	37 / 578	32%	5.83	373 / 1155
adipose	39%	69.91	464 / 1204	0%	0	0 / 0
stomach	31%	81.47	112 / 359	5%	0.47	14 / 286
eye	0%	0	0 / 0	14%	0.89	11 / 80
kidney	9%	13.37	8 / 89	4%	0.53	34 / 901
liver	0%	0.70	1 / 226	4%	0.58	18 / 406
spleen	2%	2.67	4 / 241	0%	0	0 / 0
heart	1%	1.10	7 / 861	0%	0	0 / 0
peripheral blood	1%	1.23	7 / 929	0%	0	0 / 0
muscle	0%	0.28	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071543	Biological process	diphosphoinositol polyphosphate metabolic process
GO_1901909	Biological process	diadenosine hexaphosphate catabolic process
GO_1901911	Biological process	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process
GO_1901907	Biological process	diadenosine pentaphosphate catabolic process
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0034432	Molecular function	bis(5'-adenosyl)-pentaphosphatase activity
GO_0000298	Molecular function	endopolyphosphatase activity
GO_0008486	Molecular function	diphosphoinositol-polyphosphate diphosphatase activity
GO_0034431	Molecular function	bis(5'-adenosyl)-hexaphosphatase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

Gene name	NUDT11
Protein name	Diphosphoinositol polyphosphate phosphohydrolase 3-beta (DIPP-3-beta) (DIPP3-beta) (hDIPP3beta) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta) (Diadenosine hexaphosphate hydrolase (AMP-forming)) (EC 3.6.1.60) (Nucleoside diphosphate-linked moiety X motif 11) (Nudix motif 11) (hAps1)
Synonyms	APS1 DIPP3B
Description	FUNCTION: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. .
Accessions	ENST00000375992.4 Q96G61

NUDT11 report