NUDT10 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of NUDT10 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	979.51	245 / 245	98%	18.34	492 / 502
brain	98%	715.32	2581 / 2642	97%	24.67	687 / 705
ovary	100%	1332.35	180 / 180	44%	2.56	189 / 430
uterus	99%	444.22	169 / 170	24%	3.44	111 / 459
adrenal gland	50%	61.41	129 / 258	66%	7.85	152 / 230
kidney	96%	287.65	85 / 89	10%	0.45	89 / 901
bladder	90%	341.14	19 / 21	8%	0.60	41 / 504
spleen	96%	303.24	231 / 241	0%	0	0 / 0
blood vessel	94%	189.41	1259 / 1335	0%	0	0 / 0
breast	42%	50.89	193 / 459	46%	3.29	513 / 1118
intestine	74%	169.96	711 / 966	6%	0.20	29 / 527
esophagus	42%	53.45	608 / 1445	14%	1.07	26 / 183
eye	0%	0	0 / 0	56%	3.12	45 / 80
skin	25%	32.92	451 / 1809	26%	2.80	123 / 472
stomach	40%	71.60	142 / 359	9%	0.29	25 / 286
pancreas	0%	0.31	1 / 328	35%	1.92	62 / 178
thymus	23%	28.89	147 / 653	11%	0.36	67 / 605
lung	7%	9.58	38 / 578	21%	1.80	242 / 1155
adipose	19%	19.86	225 / 1204	0%	0	0 / 0
heart	17%	22.15	150 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	16%	1.54	7 / 45
liver	13%	13.91	29 / 226	1%	0.10	6 / 406
peripheral blood	1%	0.55	5 / 929	0%	0	0 / 0
muscle	0%	0.25	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071543	Biological process	diphosphoinositol polyphosphate metabolic process
GO_1901909	Biological process	diadenosine hexaphosphate catabolic process
GO_1901911	Biological process	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process
GO_1901907	Biological process	diadenosine pentaphosphate catabolic process
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0034432	Molecular function	bis(5'-adenosyl)-pentaphosphatase activity
GO_0000298	Molecular function	endopolyphosphatase activity
GO_0008486	Molecular function	diphosphoinositol-polyphosphate diphosphatase activity
GO_0034431	Molecular function	bis(5'-adenosyl)-hexaphosphatase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

Gene name	NUDT10
Protein name	Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (DIPP-3-alpha) (DIPP3-alpha) (hDIPP3alpha) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha) (Diadenosine hexaphosphate hydrolase (AMP-forming)) (EC 3.6.1.60) (Nucleoside diphosphate-linked moiety X motif 10) (Nudix motif 10) (hAps2)
Synonyms	DIPP3A APS2
Description	FUNCTION: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. .
Accessions	ENST00000376006.7 Q8NFP7 ENST00000356450.3

NUDT10 report