NUBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001558Biological processregulation of cell growth
GO_0051642Biological processcentrosome localization
GO_0030030Biological processcell projection organization
GO_0072697Biological processprotein localization to cell cortex
GO_0016226Biological processiron-sulfur cluster assembly
GO_0006879Biological processintracellular iron ion homeostasis
GO_0010826Biological processnegative regulation of centrosome duplication
GO_0005886Cellular componentplasma membrane
GO_0005813Cellular componentcentrosome
GO_0005814Cellular componentcentriole
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0140663Molecular functionATP-dependent FeS chaperone activity
GO_0051536Molecular functioniron-sulfur cluster binding
GO_0000166Molecular functionnucleotide binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameNUBP1
Protein nameC447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) )
NUBP iron-sulfur cluster assembly factor 1, cytosolic
Cytosolic Fe-S cluster assembly factor NUBP1 (Nucleotide-binding protein 1) (NBP 1)
SynonymsNBP1
NBP
DescriptionFUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery . Required for maturation of extramitochondrial Fe-S proteins . The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins . Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity). .

AccessionsI3L518
Q2YS46
ENST00000571175.5
I3L531
I3L3A0
P53384
ENST00000574334.5
ENST00000283027.10 [P53384-1]
ENST00000433392.6 [P53384-2]
ENST00000574691.1