NT5C3B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009117Biological processnucleotide metabolic process
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0000166Molecular functionnucleotide binding
GO_0005515Molecular functionprotein binding
GO_0008253Molecular function5'-nucleotidase activity
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameNT5C3B
Protein name5'-nucleotidase, cytosolic IIIB
7-methylguanosine phosphate-specific 5'-nucleotidase (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3B) (Cytosolic 5'-nucleotidase III-like protein) (cN-III-like protein) (EC 3.1.3.5) (N(7)-methylguanylate 5'-phosphatase)
SynonymsNT5C3L
DescriptionFUNCTION: Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate . The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids . Also has weak activity for CMP . UMP and purine nucleotides are poor substrates . .

AccessionsENST00000445655.5
C9J758
ENST00000415460.5
E5RH64
U3KQB1
Q969T7
ENST00000435506.7 [Q969T7-1]
ENST00000521789.5
C9IZA4
ENST00000475053.5
E5RJR6
ENST00000486304.2