NSUN4 | OmnibusX

Name	Number of supported studies	Average coverage
brain	5 studies	21% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	1458.52	21 / 21	100%	11.26	504 / 504
breast	100%	1511.70	459 / 459	100%	14.00	1118 / 1118
esophagus	100%	1272.03	1445 / 1445	100%	10.37	183 / 183
intestine	100%	1230.91	966 / 966	100%	9.61	527 / 527
lung	100%	1386.39	578 / 578	100%	11.18	1155 / 1155
ovary	100%	1482.85	180 / 180	100%	12.69	430 / 430
prostate	100%	1643.00	245 / 245	100%	11.58	502 / 502
stomach	100%	1056.11	359 / 359	100%	8.97	286 / 286
uterus	100%	1346.35	170 / 170	100%	12.11	458 / 459
thymus	100%	1651.04	653 / 653	100%	9.99	602 / 605
pancreas	100%	886.85	328 / 328	99%	9.22	177 / 178
skin	100%	1374.37	1809 / 1809	99%	12.64	469 / 472
brain	99%	838.87	2627 / 2642	100%	9.04	703 / 705
liver	100%	789.77	226 / 226	99%	6.38	402 / 406
kidney	100%	1454.31	89 / 89	99%	10.49	888 / 901
adrenal gland	100%	2268.12	258 / 258	97%	6.74	222 / 230
adipose	100%	1438.39	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1174.36	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	12.55	29 / 29
muscle	100%	1102.23	803 / 803	0%	0	0 / 0
spleen	100%	1367.10	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	11.98	45 / 45
ureter	0%	0	0 / 0	100%	2.96	1 / 1
heart	98%	903.96	848 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	9.41	78 / 80
peripheral blood	92%	1091.57	859 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0031167	Biological process	rRNA methylation
GO_0005762	Cellular component	mitochondrial large ribosomal subunit
GO_0005759	Cellular component	mitochondrial matrix
GO_0016428	Molecular function	tRNA (cytidine-5-)-methyltransferase activity
GO_0008649	Molecular function	rRNA methyltransferase activity
GO_0019843	Molecular function	rRNA binding
GO_0005515	Molecular function	protein binding
GO_0009383	Molecular function	rRNA (cytosine-C5-)-methyltransferase activity
GO_0008168	Molecular function	methyltransferase activity

Gene name	NSUN4
Protein name	NOP2/Sun RNA methyltransferase 4 NOP2/Sun RNA methyltransferase 4 (cDNA FLJ46186 fis, clone TESTI4005013) 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4)
Synonyms
Description	FUNCTION: Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4. .
Accessions	ENST00000495427.1 A0A087WT36 M0R1K5 A0A087WUV3 ENST00000486270.5 A0A087X0V6 ENST00000469918.5 Q96CB9 Q6ZRQ1 ENST00000498008.5 ENST00000474844.6 [Q96CB9-1] ENST00000307089.7 ENST00000537428.2 [Q96CB9-4]

NSUN4 report