Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 4 studies | 26% ± 7% |
Insufficient scRNA-seq data for expression of NOXA1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1430.36 | 245 / 245 | 99% | 42.88 | 497 / 502 |
thymus | 100% | 1698.36 | 652 / 653 | 99% | 51.36 | 597 / 605 |
ovary | 99% | 1246.54 | 179 / 180 | 99% | 46.44 | 424 / 430 |
liver | 100% | 726.03 | 225 / 226 | 95% | 26.48 | 386 / 406 |
intestine | 99% | 1132.60 | 955 / 966 | 95% | 38.71 | 502 / 527 |
stomach | 99% | 952.84 | 355 / 359 | 94% | 26.85 | 268 / 286 |
kidney | 100% | 1364.94 | 89 / 89 | 92% | 29.93 | 827 / 901 |
pancreas | 100% | 1135.08 | 328 / 328 | 92% | 42.55 | 163 / 178 |
adrenal gland | 100% | 732.14 | 257 / 258 | 89% | 23.07 | 205 / 230 |
breast | 98% | 988.03 | 452 / 459 | 88% | 28.71 | 988 / 1118 |
uterus | 99% | 960.08 | 169 / 170 | 86% | 30.29 | 395 / 459 |
brain | 99% | 1201.61 | 2610 / 2642 | 83% | 17.84 | 587 / 705 |
lung | 98% | 628.97 | 568 / 578 | 83% | 21.52 | 958 / 1155 |
esophagus | 98% | 709.27 | 1413 / 1445 | 81% | 18.70 | 148 / 183 |
bladder | 95% | 683.90 | 20 / 21 | 82% | 24.56 | 415 / 504 |
skin | 71% | 434.64 | 1282 / 1809 | 31% | 4.02 | 144 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 35.48 | 1 / 1 |
spleen | 100% | 887.55 | 240 / 241 | 0% | 0 | 0 / 0 |
adipose | 94% | 440.19 | 1126 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 93% | 404.75 | 1242 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 16.08 | 36 / 45 |
heart | 77% | 282.15 | 662 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 73% | 9.98 | 58 / 80 |
muscle | 65% | 276.57 | 520 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 34% | 105.81 | 316 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 31% | 4.17 | 9 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006801 | Biological process | superoxide metabolic process |
GO_0060263 | Biological process | regulation of respiratory burst |
GO_0010310 | Biological process | regulation of hydrogen peroxide metabolic process |
GO_0042554 | Biological process | superoxide anion generation |
GO_0005829 | Cellular component | cytosol |
GO_0043020 | Cellular component | NADPH oxidase complex |
GO_0019899 | Molecular function | enzyme binding |
GO_0016176 | Molecular function | superoxide-generating NADPH oxidase activator activity |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | NOXA1 |
Protein name | NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox) NADPH oxidase activator 1 |
Synonyms | P51NOX |
Description | FUNCTION: Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. . |
Accessions | A0A804HIB1 Q86UR1 A0A804HJ29 ENST00000683555.1 [Q86UR1-1] ENST00000683683.1 ENST00000392815.2 [Q86UR1-3] ENST00000341349.6 [Q86UR1-2] ENST00000684693.1 |