NOX3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NOX3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NOX3 at tissue level.

III. Associated gene sets

GO_0006952Biological processdefense response
GO_0001659Biological processtemperature homeostasis
GO_0009590Biological processdetection of gravity
GO_0048840Biological processotolith development
GO_0042554Biological processsuperoxide anion generation
GO_0070062Cellular componentextracellular exosome
GO_0043020Cellular componentNADPH oxidase complex
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0106292Molecular functionsuperoxide-generating NADPH oxidase activity
GO_0020037Molecular functionheme binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0016175Molecular functionsuperoxide-generating NAD(P)H oxidase activity

IV. Literature review

[source]
Gene nameNOX3
Protein nameNADPH oxidase 3 (EC 1.6.3.-) (Mitogenic oxidase 2) (MOX-2) (gp91phox homolog 3) (GP91-3)
SynonymsMOX2
DescriptionFUNCTION: NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor, upon formation of a complex with CYBA/p22phox . Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity (By similarity). .

AccessionsENST00000159060.3
Q9HBY0