NMRAL1 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	6 studies	31% ± 15%	Explore
natural killer cell	4 studies	18% ± 2%	Explore
ciliated cell	4 studies	27% ± 5%	Explore
oligodendrocyte	4 studies	20% ± 3%	Explore
CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
hematopoietic precursor cell	3 studies	23% ± 4%	Explore
dendritic cell	3 studies	25% ± 3%	Explore
basal cell	3 studies	29% ± 11%	Explore
plasmacytoid dendritic cell	3 studies	19% ± 2%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	29% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1257.02	1445 / 1445	100%	30.20	183 / 183
ovary	100%	1760.13	180 / 180	100%	44.30	430 / 430
pancreas	100%	1400.32	328 / 328	100%	37.37	178 / 178
uterus	100%	1494.82	170 / 170	100%	53.71	459 / 459
thymus	100%	1846.36	653 / 653	100%	40.02	604 / 605
stomach	100%	1795.37	359 / 359	100%	36.43	285 / 286
breast	100%	1642.08	459 / 459	100%	60.03	1113 / 1118
prostate	100%	2387.31	245 / 245	99%	90.62	499 / 502
skin	100%	1809.02	1809 / 1809	99%	51.27	469 / 472
kidney	100%	1857.34	89 / 89	99%	36.81	893 / 901
bladder	100%	1321.33	21 / 21	99%	46.00	498 / 504
lung	100%	1280.71	577 / 578	99%	41.46	1143 / 1155
intestine	100%	1390.93	966 / 966	99%	42.10	520 / 527
adrenal gland	100%	2172.43	258 / 258	97%	31.67	222 / 230
liver	100%	1741.93	226 / 226	92%	37.49	373 / 406
brain	100%	1594.83	2640 / 2642	90%	33.16	638 / 705
adipose	100%	1197.90	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	58.46	80 / 80
spleen	100%	1636.86	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	45.07	45 / 45
ureter	0%	0	0 / 0	100%	68.48	1 / 1
blood vessel	100%	1175.13	1331 / 1335	0%	0	0 / 0
peripheral blood	96%	1137.70	894 / 929	0%	0	0 / 0
heart	96%	789.32	826 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	38.46	25 / 29
muscle	24%	81.41	190 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

Gene name	NMRAL1
Protein name	NmrA-like family domain-containing protein 1 NmrA like redox sensor 1 (NmrA-like family domain-containing protein 1)
Synonyms	HSCARG
Description	FUNCTION: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer. .
Accessions	ENST00000631694.1 ENST00000404295.7 ENST00000572232.5 I3L1Y8 I3L2U0 ENST00000616587.2 ENST00000621810.4 ENST00000573520.5 ENST00000571291.5 ENST00000572110.1 ENST00000633905.1 ENST00000571448.5 I3L543 ENST00000632013.1 I3L1Q7 ENST00000631867.1 ENST00000573571.1 ENST00000631933.1 ENST00000632312.1 I3L3I6 ENST00000574425.5 ENST00000633784.1 Q9HBL8 ENST00000632279.1 I3L3Z0 ENST00000633085.1 ENST00000574733.5 I3L0Y6 ENST00000576176.1 ENST00000283429.11

GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005634	Cellular component	nucleus
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

NMRAL1 report