NLRP7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NLRP7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NLRP7 at tissue level.

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_1900016Biological processnegative regulation of cytokine production involved in inflammatory response
GO_0071347Biological processcellular response to interleukin-1
GO_0010955Biological processnegative regulation of protein processing
GO_0050727Biological processregulation of inflammatory response
GO_0032691Biological processnegative regulation of interleukin-1 beta production
GO_0005575Cellular componentcellular_component
GO_0005737Cellular componentcytoplasm
GO_0089720Molecular functioncaspase binding
GO_0019828Molecular functionaspartic-type endopeptidase inhibitor activity
GO_0019966Molecular functioninterleukin-1 binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameNLRP7
Protein nameNACHT, LRR and PYD domains-containing protein 7 (NLR family pyrin domain containing 7)
NACHT, LRR and PYD domains-containing protein 7
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)
NLRP7 protein
SynonymsNOD12
PYPAF3
NALP7
DescriptionFUNCTION: Inhibits CASP1/caspase-1-dependent IL1B secretion. .

AccessionsENST00000610981.4 [Q8WX94-3]
Q32MH9
ENST00000615699.1 [Q8WX94-1]
A0A0G2JNS7
ENST00000621787.2
ENST00000587844.1
ENST00000615426.4 [Q8WX94-3]
ENST00000614922.3
ENST00000622467.4
ENST00000618995.1 [Q8WX94-1]
ENST00000619082.4
ENST00000622173.4
ENST00000618592.4
ENST00000610853.4 [Q8WX94-2]
ENST00000586379.5
ENST00000621903.4
ENST00000618672.4 [Q8WX94-3]
ENST00000328092.9 [Q8WX94-2]
ENST00000340844.6 [Q8WX94-1]
ENST00000620334.4
ENST00000613325.4
ENST00000620183.1 [Q8WX94-1]
ENST00000613487.4
ENST00000611597.4 [Q8WX94-1]
ENST00000587103.5
A0A0G2JPH3
K7ER92
ENST00000618343.4 [Q8WX94-3]
ENST00000592784.6 [Q8WX94-3]
A0A0G2JM63
K7EPY3
ENST00000621238.4 [Q8WX94-3]
ENST00000620820.4 [Q8WX94-3]
Q8WX94
ENST00000621584.1 [Q8WX94-1]
ENST00000622199.4 [Q8WX94-3]
ENST00000590030.5 [Q8WX94-1]
ENST00000610424.4 [Q8WX94-3]
A0A0G2JNI8
K7EP54
ENST00000618261.1 [Q8WX94-1]
ENST00000590659.1
A0A0G2JNK3
K7ERG0
ENST00000610790.1 [Q8WX94-1]
A0A0G2JMB6
A0A0G2JNK1
ENST00000618740.4 [Q8WX94-3]
ENST00000619096.4
A0A0G2JM25
ENST00000613233.1 [Q8WX94-1]
ENST00000614879.1 [Q8WX94-1]
ENST00000615467.4
ENST00000588756.5 [Q8WX94-3]