NLE1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NLE1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NLE1 at tissue level.

III. Associated gene sets

GO_0042273Biological processribosomal large subunit biogenesis
GO_0001822Biological processkidney development
GO_0001826Biological processinner cell mass cell differentiation
GO_0000027Biological processribosomal large subunit assembly
GO_0045930Biological processnegative regulation of mitotic cell cycle
GO_0000278Biological processmitotic cell cycle
GO_0007219Biological processNotch signaling pathway
GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0061484Biological processhematopoietic stem cell homeostasis
GO_0001756Biological processsomitogenesis
GO_0048705Biological processskeletal system morphogenesis
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm

IV. Literature review

[source]
Gene nameNLE1
Protein nameNotchless protein homolog 1
Notchless homolog 1
SynonymsHUSSY-07
DescriptionFUNCTION: Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity). .

AccessionsENST00000586869.5 [Q9NVX2-2]
A0A0A0MRH0
K7EK23
Q9NVX2
ENST00000360831.9
ENST00000588019.1
K7ERN7
K7EN33
ENST00000588642.1
ENST00000589367.5
ENST00000442241.9 [Q9NVX2-1]