Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 30% ± 7% | |
dendritic cell | 3 studies | 23% ± 2% |
Insufficient scRNA-seq data for expression of NFKBIL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 697.74 | 226 / 226 | 100% | 39.48 | 406 / 406 |
ovary | 100% | 1751.87 | 180 / 180 | 100% | 33.24 | 430 / 430 |
thymus | 100% | 1424.06 | 653 / 653 | 100% | 51.43 | 605 / 605 |
brain | 100% | 921.13 | 2639 / 2642 | 100% | 52.24 | 705 / 705 |
skin | 100% | 1131.09 | 1809 / 1809 | 100% | 52.21 | 471 / 472 |
uterus | 100% | 1371.16 | 170 / 170 | 100% | 45.51 | 458 / 459 |
adrenal gland | 100% | 989.53 | 258 / 258 | 100% | 40.73 | 229 / 230 |
esophagus | 100% | 1122.60 | 1445 / 1445 | 99% | 16.36 | 182 / 183 |
kidney | 100% | 1044.12 | 89 / 89 | 99% | 31.02 | 896 / 901 |
pancreas | 100% | 1322.57 | 328 / 328 | 99% | 34.63 | 177 / 178 |
prostate | 100% | 1452.13 | 245 / 245 | 99% | 58.86 | 499 / 502 |
intestine | 100% | 1211.11 | 966 / 966 | 98% | 26.37 | 518 / 527 |
bladder | 100% | 1300.38 | 21 / 21 | 98% | 37.07 | 495 / 504 |
breast | 100% | 1260.86 | 459 / 459 | 97% | 35.53 | 1090 / 1118 |
lung | 100% | 984.41 | 577 / 578 | 98% | 28.67 | 1128 / 1155 |
stomach | 100% | 1296.79 | 359 / 359 | 97% | 21.53 | 277 / 286 |
adipose | 100% | 1091.57 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 123.21 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 35.17 | 29 / 29 |
spleen | 100% | 1136.92 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 35.53 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 63.12 | 1 / 1 |
blood vessel | 100% | 1200.48 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 894.18 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 644.83 | 851 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 795.42 | 909 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071222 | Biological process | cellular response to lipopolysaccharide |
GO_0032720 | Biological process | negative regulation of tumor necrosis factor production |
GO_0043124 | Biological process | negative regulation of canonical NF-kappaB signal transduction |
GO_0032088 | Biological process | negative regulation of NF-kappaB transcription factor activity |
GO_0034122 | Biological process | negative regulation of toll-like receptor signaling pathway |
GO_0031665 | Biological process | negative regulation of lipopolysaccharide-mediated signaling pathway |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0140416 | Molecular function | transcription regulator inhibitor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | NFKBIL1 |
Protein name | NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) |
Synonyms | IKBL hCG_43682 |
Description | FUNCTION: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. . |
Accessions | ENST00000400285.7 ENST00000430961.6 ENST00000400279.7 ENST00000414391.6 ENST00000460131.1 Q5STV6 ENST00000430501.2 ENST00000421396.2 A0A286SD72 A0A286SD75 A0A286SD77 ENST00000442947.6 A0A0A0MRT5 ENST00000451911.2 ENST00000455376.6 ENST00000434332.6 ENST00000496233.1 ENST00000468464.1 ENST00000376145.8 [Q9UBC1-3] ENST00000456607.6 A0A286SD76 ENST00000376148.9 [Q9UBC1-1] ENST00000453377.6 A0A286SD81 Q9UBC1 ENST00000432160.6 ENST00000376146.8 ENST00000419623.6 ENST00000376146.8 [Q9UBC1-2] ENST00000376145.8 ENST00000383500.4 A0A140TA04 F2Z390 ENST00000428467.6 ENST00000419122.6 ENST00000424652.6 Q5ST97 |