NFKBIL1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NFKBIL1 at tissue level.

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_0032720Biological processnegative regulation of tumor necrosis factor production
GO_0043124Biological processnegative regulation of canonical NF-kappaB signal transduction
GO_0032088Biological processnegative regulation of NF-kappaB transcription factor activity
GO_0034122Biological processnegative regulation of toll-like receptor signaling pathway
GO_0031665Biological processnegative regulation of lipopolysaccharide-mediated signaling pathway
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0140416Molecular functiontranscription regulator inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNFKBIL1
Protein nameNF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)
NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)
SynonymsIKBL
hCG_43682
DescriptionFUNCTION: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. .

AccessionsENST00000400285.7
ENST00000430961.6
ENST00000400279.7
ENST00000414391.6
ENST00000460131.1
Q5STV6
ENST00000430501.2
ENST00000421396.2
A0A286SD72
A0A286SD75
A0A286SD77
ENST00000442947.6
A0A0A0MRT5
ENST00000451911.2
ENST00000455376.6
ENST00000434332.6
ENST00000496233.1
ENST00000468464.1
ENST00000376145.8 [Q9UBC1-3]
ENST00000456607.6
A0A286SD76
ENST00000376148.9 [Q9UBC1-1]
ENST00000453377.6
A0A286SD81
Q9UBC1
ENST00000432160.6
ENST00000376146.8
ENST00000419623.6
ENST00000376146.8 [Q9UBC1-2]
ENST00000376145.8
ENST00000383500.4
A0A140TA04
F2Z390
ENST00000428467.6
ENST00000419122.6
ENST00000424652.6
Q5ST97