I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 4 studies | 22% ± 7% | |
| conventional dendritic cell | 3 studies | 23% ± 6% | |
| myeloid cell | 3 studies | 26% ± 7% | |
| mononuclear phagocyte | 3 studies | 22% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 4 studies | 22% ± 7% | |
| conventional dendritic cell | 3 studies | 23% ± 6% | |
| myeloid cell | 3 studies | 26% ± 7% | |
| mononuclear phagocyte | 3 studies | 22% ± 6% |
Insufficient scRNA-seq data for expression of NFKBIE at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 701.02 | 1808 / 1809 | 100% | 72.35 | 471 / 472 |
| intestine | 100% | 604.11 | 966 / 966 | 99% | 32.93 | 524 / 527 |
| lung | 100% | 1117.98 | 578 / 578 | 99% | 32.53 | 1147 / 1155 |
| brain | 99% | 540.76 | 2618 / 2642 | 100% | 23.76 | 705 / 705 |
| prostate | 100% | 687.35 | 245 / 245 | 99% | 20.80 | 496 / 502 |
| bladder | 100% | 514.00 | 21 / 21 | 99% | 37.00 | 497 / 504 |
| stomach | 100% | 495.42 | 359 / 359 | 99% | 30.97 | 282 / 286 |
| uterus | 99% | 345.39 | 169 / 170 | 99% | 35.82 | 455 / 459 |
| breast | 100% | 548.09 | 458 / 459 | 99% | 30.51 | 1102 / 1118 |
| esophagus | 100% | 375.05 | 1442 / 1445 | 98% | 27.22 | 180 / 183 |
| thymus | 100% | 473.58 | 652 / 653 | 98% | 24.57 | 590 / 605 |
| kidney | 100% | 1054.18 | 89 / 89 | 97% | 42.30 | 871 / 901 |
| pancreas | 97% | 412.99 | 319 / 328 | 99% | 41.42 | 176 / 178 |
| liver | 99% | 433.13 | 223 / 226 | 91% | 27.14 | 368 / 406 |
| ovary | 90% | 219.33 | 162 / 180 | 98% | 26.97 | 422 / 430 |
| adrenal gland | 99% | 455.17 | 256 / 258 | 86% | 13.91 | 197 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 197.57 | 29 / 29 |
| spleen | 100% | 2849.98 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 42.61 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 19.41 | 1 / 1 |
| adipose | 100% | 502.84 | 1198 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 2784.27 | 921 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 25.15 | 78 / 80 |
| blood vessel | 96% | 333.25 | 1277 / 1335 | 0% | 0 | 0 / 0 |
| heart | 89% | 265.09 | 765 / 861 | 0% | 0 | 0 / 0 |
| muscle | 71% | 159.42 | 570 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042994 | Biological process | cytoplasmic sequestering of transcription factor |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NFKBIE |
| Protein name | NFKBIE protein NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon) NFKB inhibitor epsilon NFKB inhibitor epsilon (NFKBIE protein) (cDNA FLJ61640, highly similar to NF-kappa-B inhibitor epsilon) |
| Synonyms | IKBE |
| Description | FUNCTION: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. . |
| Accessions | ENST00000275015.9 ENST00000477930.2 Q96F31 H0Y4W4 Q7LC14 ENST00000443607.2 ENST00000619360.6 O00221 H3BNC2 |
