Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 8 studies | 41% ± 21% | |
epithelial cell | 6 studies | 29% ± 11% | |
ciliated cell | 5 studies | 23% ± 4% | |
GABAergic neuron | 5 studies | 40% ± 18% | |
astrocyte | 5 studies | 27% ± 7% | |
interneuron | 5 studies | 33% ± 21% | |
oligodendrocyte | 5 studies | 21% ± 4% | |
neuron | 4 studies | 23% ± 6% | |
endothelial cell | 4 studies | 29% ± 11% | |
oligodendrocyte precursor cell | 4 studies | 21% ± 5% | |
abnormal cell | 3 studies | 18% ± 2% | |
ependymal cell | 3 studies | 44% ± 1% | |
transit amplifying cell | 3 studies | 23% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2370.29 | 1445 / 1445 | 100% | 23.23 | 183 / 183 |
ovary | 100% | 3113.99 | 180 / 180 | 100% | 36.67 | 430 / 430 |
uterus | 100% | 2713.13 | 170 / 170 | 100% | 31.43 | 459 / 459 |
thymus | 100% | 2559.09 | 653 / 653 | 100% | 33.82 | 604 / 605 |
brain | 100% | 1860.85 | 2635 / 2642 | 100% | 30.84 | 705 / 705 |
stomach | 100% | 1599.98 | 359 / 359 | 100% | 26.84 | 285 / 286 |
intestine | 100% | 2162.63 | 966 / 966 | 100% | 31.23 | 525 / 527 |
bladder | 100% | 2303.24 | 21 / 21 | 100% | 33.21 | 502 / 504 |
pancreas | 100% | 1427.80 | 328 / 328 | 99% | 25.81 | 177 / 178 |
prostate | 100% | 2346.59 | 245 / 245 | 99% | 26.18 | 499 / 502 |
lung | 100% | 1771.66 | 577 / 578 | 100% | 24.58 | 1150 / 1155 |
skin | 100% | 2694.37 | 1809 / 1809 | 99% | 29.89 | 468 / 472 |
adrenal gland | 100% | 1847.55 | 258 / 258 | 99% | 18.78 | 228 / 230 |
breast | 100% | 2316.16 | 459 / 459 | 99% | 23.87 | 1107 / 1118 |
kidney | 100% | 1884.09 | 89 / 89 | 99% | 18.32 | 892 / 901 |
liver | 100% | 982.22 | 226 / 226 | 95% | 12.99 | 386 / 406 |
adipose | 100% | 1930.62 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 28.36 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 24.38 | 29 / 29 |
spleen | 100% | 2388.23 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 28.42 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 22.89 | 1 / 1 |
blood vessel | 100% | 1909.15 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 1134.39 | 798 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 994.32 | 848 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 90% | 1182.84 | 833 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034244 | Biological process | negative regulation of transcription elongation by RNA polymerase II |
GO_0031401 | Biological process | positive regulation of protein modification process |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0032021 | Cellular component | NELF complex |
GO_0016604 | Cellular component | nuclear body |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0060090 | Molecular function | molecular adaptor activity |
Gene name | NELFA |
Protein name | Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein) Negative elongation factor complex member A |
Synonyms | P/OKcl.15 WHSC2 |
Description | FUNCTION: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. .; FUNCTION: (Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. . |
Accessions | H7C2C7 A0A0C4DFX9 H0Y3X6 F8W954 ENST00000416258.5 ENST00000333877.8 C9JHL4 ENST00000382882.9 [Q9H3P2-1] ENST00000443203.5 H7C0W2 ENST00000411649.3 ENST00000421397.5 F8WF98 ENST00000458616.1 C9JEM7 ENST00000455762.5 H7C3C2 ENST00000431323.6 ENST00000542778.5 Q9H3P2 ENST00000453740.5 H7C2M8 |