NEK11 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	18 studies	44% ± 20%	Explore
astrocyte	12 studies	32% ± 19%	Explore
glutamatergic neuron	9 studies	40% ± 28%	Explore
GABAergic neuron	4 studies	49% ± 20%	Explore
endothelial cell	3 studies	28% ± 9%	Explore
epithelial cell	3 studies	32% ± 20%	Explore
oligodendrocyte precursor cell	3 studies	25% ± 4%	Explore
ependymal cell	3 studies	78% ± 9%	Explore
adipocyte	3 studies	17% ± 1%	Explore
interneuron	3 studies	55% ± 26%	Explore
oligodendrocyte	3 studies	30% ± 18%	Explore

Name	Number of supported studies	Average coverage
brain	9 studies	35% ± 21%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	771.30	2635 / 2642	99%	14.02	699 / 705
ovary	100%	571.24	180 / 180	98%	8.94	420 / 430
breast	99%	525.98	455 / 459	98%	12.74	1096 / 1118
prostate	100%	397.33	244 / 245	97%	5.67	486 / 502
thymus	100%	1061.44	653 / 653	95%	9.38	573 / 605
uterus	100%	471.76	170 / 170	92%	7.46	421 / 459
kidney	100%	558.99	89 / 89	91%	9.61	817 / 901
bladder	100%	352.38	21 / 21	89%	4.60	449 / 504
pancreas	92%	197.52	301 / 328	95%	5.90	169 / 178
lung	98%	516.28	565 / 578	87%	5.41	1000 / 1155
esophagus	97%	292.14	1408 / 1445	78%	3.83	143 / 183
intestine	98%	289.45	942 / 966	77%	3.49	405 / 527
skin	99%	363.84	1784 / 1809	65%	2.82	308 / 472
adrenal gland	99%	644.97	255 / 258	60%	2.75	137 / 230
stomach	74%	154.28	265 / 359	76%	3.42	217 / 286
ureter	0%	0	0 / 0	100%	5.06	1 / 1
adipose	99%	373.95	1190 / 1204	0%	0	0 / 0
blood vessel	96%	264.06	1288 / 1335	0%	0	0 / 0
spleen	92%	169.43	221 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	5.28	37 / 45
heart	68%	146.22	588 / 861	0%	0	0 / 0
muscle	48%	77.74	386 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	26%	0.98	21 / 80
liver	8%	9.96	17 / 226	16%	0.92	65 / 406
peripheral blood	4%	5.13	34 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.09	1 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0031573	Biological process	mitotic intra-S DNA damage checkpoint signaling
GO_0035556	Biological process	intracellular signal transduction
GO_0006468	Biological process	protein phosphorylation
GO_1901990	Biological process	regulation of mitotic cell cycle phase transition
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0004674	Molecular function	protein serine/threonine kinase activity
GO_0106310	Molecular function	protein serine kinase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding

Gene name	NEK11
Protein name	non-specific serine/threonine protein kinase (EC 2.7.11.1) NIMA related kinase 11 Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)
Synonyms
Description	FUNCTION: Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. .
Accessions	D6RJF7 ENST00000514915.5 Q8NG66 A0A075B7B3 ENST00000602792.1 ENST00000510769.5 ENST00000511262.5 [Q8NG66-2] ENST00000356918.8 [Q8NG66-2] ENST00000508196.5 [Q8NG66-1] ENST00000510474.5 ENST00000383366.9 [Q8NG66-1] ENST00000507910.5 [Q8NG66-3] D6RGV6 ENST00000510688.5 [Q8NG66-4] E9PHI8

NEK11 report