Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 18 studies | 50% ± 22% | |
| glutamatergic neuron | 9 studies | 50% ± 24% | |
| GABAergic neuron | 6 studies | 56% ± 23% | |
| cardiac muscle cell | 5 studies | 34% ± 8% | |
| retinal cone cell | 5 studies | 30% ± 10% | |
| microglial cell | 4 studies | 18% ± 2% | |
| interneuron | 4 studies | 52% ± 22% | |
| neuron | 3 studies | 22% ± 4% | |
| GABAergic interneuron | 3 studies | 32% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 69% | 517.07 | 319 / 459 | 62% | 6.74 | 697 / 1118 |
| prostate | 95% | 176.71 | 232 / 245 | 20% | 0.30 | 99 / 502 |
| bladder | 95% | 164.19 | 20 / 21 | 8% | 0.24 | 41 / 504 |
| muscle | 98% | 394.04 | 790 / 803 | 0% | 0 | 0 / 0 |
| stomach | 90% | 89.62 | 323 / 359 | 4% | 0.08 | 11 / 286 |
| heart | 94% | 269.59 | 806 / 861 | 0% | 0 | 0 / 0 |
| intestine | 87% | 159.34 | 838 / 966 | 1% | 0.02 | 6 / 527 |
| brain | 78% | 200.75 | 2048 / 2642 | 9% | 0.21 | 65 / 705 |
| lung | 75% | 282.13 | 432 / 578 | 11% | 0.34 | 126 / 1155 |
| kidney | 66% | 73.83 | 59 / 89 | 12% | 0.25 | 111 / 901 |
| ovary | 66% | 49.33 | 118 / 180 | 5% | 0.12 | 23 / 430 |
| thymus | 64% | 46.17 | 415 / 653 | 0% | 0.00 | 2 / 605 |
| spleen | 59% | 38.68 | 143 / 241 | 0% | 0 | 0 / 0 |
| liver | 45% | 56.66 | 102 / 226 | 10% | 0.17 | 40 / 406 |
| esophagus | 49% | 34.67 | 714 / 1445 | 3% | 0.04 | 5 / 183 |
| blood vessel | 52% | 36.90 | 691 / 1335 | 0% | 0 | 0 / 0 |
| skin | 44% | 53.89 | 789 / 1809 | 4% | 0.06 | 17 / 472 |
| adrenal gland | 20% | 11.75 | 52 / 258 | 6% | 0.09 | 14 / 230 |
| uterus | 20% | 46.84 | 34 / 170 | 5% | 0.16 | 25 / 459 |
| adipose | 20% | 13.89 | 241 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 8% | 3.96 | 26 / 328 | 6% | 0.09 | 10 / 178 |
| peripheral blood | 4% | 2.56 | 34 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0043406 | Biological process | positive regulation of MAP kinase activity |
| GO_1902749 | Biological process | regulation of cell cycle G2/M phase transition |
| GO_0031954 | Biological process | positive regulation of protein autophosphorylation |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0120197 | Biological process | mucociliary clearance |
| GO_0070372 | Biological process | regulation of ERK1 and ERK2 cascade |
| GO_0005576 | Cellular component | extracellular region |
| GO_1902911 | Cellular component | protein kinase complex |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004672 | Molecular function | protein kinase activity |
| Gene name | NEK10 |
| Protein name | Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10) NIMA related kinase 10 |
| Synonyms | |
| Description | FUNCTION: Plays a role in the cellular response to UV irradiation. Mediates G2/M cell cycle arrest, MEK autoactivation and ERK1/2-signaling pathway activation in response to UV irradiation. In ciliated cells of airways, it is involved in the regulation of mucociliary transport . . |
| Accessions | ENST00000383771.8 [Q6ZWH5-6] ENST00000435750.1 A0A8I5KTB8 C9JJN0 ENST00000435584.5 H7C000 H7C3L8 ENST00000691995.1 ENST00000341435.9 [Q6ZWH5-4] ENST00000429845.6 [Q6ZWH5-1] ENST00000295720.10 [Q6ZWH5-5] ENST00000424275.1 Q6ZWH5 |
