I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 28% ± 6% | |
| astrocyte | 3 studies | 31% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 28% ± 6% | |
| astrocyte | 3 studies | 31% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 23% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 85% | 427.51 | 494 / 578 | 29% | 0.83 | 330 / 1155 |
| liver | 73% | 388.82 | 165 / 226 | 38% | 2.82 | 154 / 406 |
| thymus | 89% | 1056.63 | 583 / 653 | 18% | 1.12 | 108 / 605 |
| brain | 84% | 439.59 | 2220 / 2642 | 20% | 0.37 | 142 / 705 |
| prostate | 88% | 2235.02 | 215 / 245 | 16% | 2.31 | 79 / 502 |
| esophagus | 48% | 413.82 | 698 / 1445 | 55% | 2.19 | 100 / 183 |
| adrenal gland | 100% | 1069.16 | 257 / 258 | 2% | 0.03 | 5 / 230 |
| muscle | 100% | 755516.58 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.76 | 1 / 1 |
| spleen | 86% | 455.37 | 207 / 241 | 0% | 0 | 0 / 0 |
| heart | 85% | 2832.21 | 733 / 861 | 0% | 0 | 0 / 0 |
| skin | 80% | 988.75 | 1443 / 1809 | 3% | 0.05 | 15 / 472 |
| pancreas | 41% | 129.02 | 136 / 328 | 35% | 1.90 | 62 / 178 |
| blood vessel | 76% | 576.45 | 1017 / 1335 | 0% | 0 | 0 / 0 |
| breast | 65% | 470.71 | 300 / 459 | 4% | 0.31 | 43 / 1118 |
| adipose | 68% | 315.79 | 824 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 45% | 207.43 | 40 / 89 | 17% | 1.26 | 149 / 901 |
| stomach | 32% | 95.63 | 116 / 359 | 27% | 1.62 | 76 / 286 |
| intestine | 42% | 166.39 | 407 / 966 | 15% | 0.67 | 77 / 527 |
| uterus | 28% | 75.33 | 47 / 170 | 11% | 1.78 | 50 / 459 |
| ovary | 33% | 122.86 | 59 / 180 | 4% | 0.07 | 19 / 430 |
| peripheral blood | 34% | 210.28 | 317 / 929 | 0% | 0 | 0 / 0 |
| bladder | 10% | 16.86 | 2 / 21 | 18% | 0.45 | 90 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 20% | 3.11 | 9 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.09 | 2 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030832 | Biological process | regulation of actin filament length |
| GO_0007525 | Biological process | somatic muscle development |
| GO_0071691 | Biological process | cardiac muscle thin filament assembly |
| GO_0007517 | Biological process | muscle organ development |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0030018 | Cellular component | Z disc |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008307 | Molecular function | structural constituent of muscle |
| Gene name | NEB |
| Protein name | Nebulin NEB protein |
| Synonyms | |
| Description | FUNCTION: This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. Binds and stabilize F-actin. |
| Accessions | ENST00000397345.8 [P20929-2] Q9Y5Z1 E2QBU3 H0Y786 H7BZD5 H0Y3P5 ENST00000693286.1 ENST00000690043.1 ENST00000421461.6 P20929 ENST00000409198.5 [P20929-4] ENST00000413693.5 A0A8I5KS37 Q6P516 H7C2B3 Q7Z2R0 Q6PJ54 ENST00000397337.6 H7C2Z5 ENST00000427231.7 [P20929-3] ENST00000424585.1 Q86TG3 ENST00000434685.6 A0A8I5QJN4 ENST00000688578.1 A0A8I5KYD3 Q05C45 |
