NDOR1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of NDOR1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1024.33	1445 / 1445	100%	33.86	183 / 183
uterus	100%	1204.46	170 / 170	100%	22.95	458 / 459
ovary	100%	986.41	180 / 180	100%	26.39	428 / 430
intestine	100%	1219.45	966 / 966	99%	21.14	524 / 527
prostate	100%	1494.51	245 / 245	99%	16.43	499 / 502
skin	100%	1147.12	1809 / 1809	99%	22.85	469 / 472
thymus	100%	1647.27	653 / 653	99%	16.26	600 / 605
stomach	100%	981.44	359 / 359	99%	23.99	283 / 286
breast	100%	1082.97	459 / 459	99%	20.31	1106 / 1118
brain	99%	845.34	2617 / 2642	100%	25.79	704 / 705
pancreas	100%	718.96	327 / 328	99%	16.93	176 / 178
bladder	100%	1126.48	21 / 21	98%	18.29	494 / 504
lung	100%	1329.62	578 / 578	98%	19.51	1132 / 1155
kidney	100%	1144.60	89 / 89	96%	11.85	866 / 901
adrenal gland	100%	1122.31	258 / 258	96%	12.54	220 / 230
liver	100%	547.75	225 / 226	87%	9.66	352 / 406
adipose	100%	949.01	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	19.36	80 / 80
lymph node	0%	0	0 / 0	100%	26.36	29 / 29
spleen	100%	2070.98	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	23.11	45 / 45
ureter	0%	0	0 / 0	100%	19.03	1 / 1
blood vessel	100%	868.43	1333 / 1335	0%	0	0 / 0
peripheral blood	99%	1320.20	918 / 929	0%	0	0 / 0
heart	98%	563.33	847 / 861	0%	0	0 / 0
muscle	88%	334.71	703 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0022900	Biological process	electron transport chain
GO_0016226	Biological process	iron-sulfur cluster assembly
GO_0045111	Cellular component	intermediate filament cytoskeleton
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005737	Cellular component	cytoplasm
GO_0071949	Molecular function	FAD binding
GO_0050661	Molecular function	NADP binding
GO_0016731	Molecular function	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
GO_0070402	Molecular function	NADPH binding
GO_0016491	Molecular function	oxidoreductase activity
GO_0016653	Molecular function	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
GO_0010181	Molecular function	FMN binding
GO_0050660	Molecular function	flavin adenine dinucleotide binding
GO_0005515	Molecular function	protein binding
GO_0009055	Molecular function	electron transfer activity
GO_0003958	Molecular function	NADPH-hemoprotein reductase activity

Gene name	NDOR1
Protein name	NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase) (Novel reductase 1)
Synonyms	NR1
Description	FUNCTION: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery . Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery . In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins . It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair . In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A . .
Accessions	Q9UHB4 ENST00000371521.8 [Q9UHB4-2] ENST00000458322.2 [Q9UHB4-4] ENST00000684003.1 [Q9UHB4-1] ENST00000427047.6 [Q9UHB4-3]

NDOR1 report