Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 35% ± 11% | |
| astrocyte | 4 studies | 20% ± 5% | |
| GABAergic neuron | 3 studies | 32% ± 2% | |
| transit amplifying cell | 3 studies | 40% ± 19% | |
| natural killer cell | 3 studies | 18% ± 4% | |
| interneuron | 3 studies | 33% ± 14% | |
| oligodendrocyte | 3 studies | 21% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 4497.47 | 245 / 245 | 100% | 135.58 | 502 / 502 |
| esophagus | 100% | 1123.01 | 1444 / 1445 | 100% | 17.04 | 183 / 183 |
| ovary | 100% | 880.08 | 180 / 180 | 99% | 11.52 | 427 / 430 |
| stomach | 100% | 1017.17 | 359 / 359 | 99% | 15.22 | 283 / 286 |
| intestine | 100% | 1137.70 | 966 / 966 | 98% | 14.66 | 519 / 527 |
| breast | 100% | 1213.45 | 459 / 459 | 98% | 13.25 | 1101 / 1118 |
| lung | 100% | 1312.68 | 578 / 578 | 98% | 12.87 | 1135 / 1155 |
| bladder | 100% | 1018.33 | 21 / 21 | 97% | 12.52 | 491 / 504 |
| uterus | 100% | 1095.36 | 170 / 170 | 97% | 13.93 | 445 / 459 |
| brain | 98% | 826.08 | 2591 / 2642 | 99% | 10.59 | 697 / 705 |
| thymus | 100% | 1632.47 | 653 / 653 | 96% | 8.48 | 578 / 605 |
| skin | 100% | 2268.50 | 1809 / 1809 | 94% | 10.71 | 444 / 472 |
| pancreas | 99% | 635.73 | 324 / 328 | 93% | 6.70 | 165 / 178 |
| adrenal gland | 100% | 1256.55 | 258 / 258 | 85% | 7.70 | 196 / 230 |
| kidney | 100% | 842.30 | 89 / 89 | 74% | 4.14 | 670 / 901 |
| liver | 100% | 992.02 | 226 / 226 | 52% | 2.98 | 212 / 406 |
| adipose | 100% | 1053.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.12 | 29 / 29 |
| spleen | 100% | 1686.46 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 13.55 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.80 | 1 / 1 |
| blood vessel | 100% | 983.90 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 96% | 498.74 | 774 / 803 | 0% | 0 | 0 / 0 |
| heart | 94% | 643.74 | 809 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 76% | 1826.29 | 710 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 66% | 3.61 | 53 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1905820 | Biological process | positive regulation of chromosome separation |
| GO_0007076 | Biological process | mitotic chromosome condensation |
| GO_1905821 | Biological process | positive regulation of chromosome condensation |
| GO_0051301 | Biological process | cell division |
| GO_0010032 | Biological process | meiotic chromosome condensation |
| GO_0051984 | Biological process | positive regulation of chromosome segregation |
| GO_0000796 | Cellular component | condensin complex |
| GO_0000779 | Cellular component | condensed chromosome, centromeric region |
| GO_0000794 | Cellular component | condensed nuclear chromosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005721 | Cellular component | pericentric heterochromatin |
| GO_0016020 | Cellular component | membrane |
| GO_0035064 | Molecular function | methylated histone binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0042393 | Molecular function | histone binding |
| Gene name | NCAPD3 |
| Protein name | Non-SMC condensin II complex subunit D3 Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) Condensin-2 complex subunit D3 NCAPD3 protein |
| Synonyms | KIAA0056 hCG_37608 CAPD3 hCAP-D3 |
| Description | FUNCTION: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis . May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size . . FUNCTION: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. . FUNCTION: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. . |
| Accessions | A0A8I5KRL1 ENST00000686368.1 ENST00000534532.7 A0A8I5QKW0 ENST00000525964.7 ENST00000532445.2 ENST00000688263.1 ENST00000526422.2 ENST00000533155.6 G3V1A9 ENST00000530396.2 ENST00000687965.1 ENST00000693576.1 ENST00000689387.1 ENST00000527944.2 ENST00000685324.1 P42695 A0A8I5QL00 ENST00000688672.1 E9PL95 ENST00000691025.1 ENST00000690743.1 A0A8I5QKQ4 A0A8I5KTC8 Q96FA6 A0A8I5KTD5 ENST00000690149.1 A0A8I5KR13 A0A8I5KYN6 A0A8I5QKI5 ENST00000526787.3 ENST00000689205.1 E9PKK4 A0A8I5KT00 E9PQA3 ENST00000534548.7 E9PLE0 E9PJM8 |
