NAT2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NAT2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NAT2 at tissue level.

III. Associated gene sets

GO_0006805Biological processxenobiotic metabolic process
GO_0005829Cellular componentcytosol
GO_0004060Molecular functionarylamine N-acetyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0046990Molecular functionN-hydroxyarylamine O-acetyltransferase activity

IV. Literature review

[source]
Gene nameNAT2
Protein nameArylamine N-acetyltransferase 2 (EC 2.3.1.5)
arylamine N-acetyltransferase (EC 2.3.1.5)
Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2) (Polymorphic arylamine N-acetyltransferase) (PNAT)
SynonymshCG_27151
AAC2
DescriptionFUNCTION: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

AccessionsA4Z6T9
A4Z6U9
P11245
E7EWF9
A4Z7H3
A4Z6V9
A4Z6Y3
A4Z6U6
A4Z7P9
A0A0S2A4Q6
A4Z6Y1
A9X816
A4Z7V0
A9X854
A4Z867
Q400I5
A9X868
A4Z6T8
A4Z787
A4Z7K4
ENST00000286479.4
A4Z737
A0A0S2A5S1
A0A0S2A5X5
A4Z7F6
Q400I7
A4Z6Y5
A9X7U6
A4Z6T7
A4Z6U4
A4Z7J7
A9X7X6
A9X844
A4Z6U7
ENST00000520116.1
A9X7Q9
A0A0S2A5J2