Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 12 studies | 27% ± 11% | |
non-classical monocyte | 11 studies | 30% ± 13% | |
epithelial cell | 9 studies | 34% ± 16% | |
enterocyte | 6 studies | 37% ± 14% | |
plasmacytoid dendritic cell | 6 studies | 22% ± 4% | |
endothelial cell | 5 studies | 25% ± 9% | |
macrophage | 5 studies | 27% ± 7% | |
squamous epithelial cell | 4 studies | 41% ± 21% | |
conventional dendritic cell | 4 studies | 36% ± 16% | |
goblet cell | 4 studies | 23% ± 4% | |
dendritic cell | 4 studies | 31% ± 15% | |
monocyte | 4 studies | 21% ± 4% | |
secretory cell | 3 studies | 23% ± 6% | |
hematopoietic precursor cell | 3 studies | 27% ± 8% | |
epithelial cell of proximal tubule | 3 studies | 17% ± 1% | |
transit amplifying cell | 3 studies | 18% ± 1% | |
myeloid cell | 3 studies | 26% ± 3% | |
progenitor cell | 3 studies | 25% ± 6% | |
ciliated cell | 3 studies | 29% ± 7% | |
basal cell | 3 studies | 37% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 4282.42 | 226 / 226 | 99% | 59.95 | 403 / 406 |
intestine | 99% | 2468.68 | 961 / 966 | 99% | 67.04 | 521 / 527 |
esophagus | 100% | 2382.15 | 1439 / 1445 | 98% | 45.18 | 180 / 183 |
stomach | 100% | 2009.77 | 359 / 359 | 98% | 60.32 | 280 / 286 |
bladder | 100% | 1806.00 | 21 / 21 | 96% | 52.51 | 484 / 504 |
uterus | 99% | 1442.82 | 169 / 170 | 96% | 50.27 | 442 / 459 |
thymus | 98% | 1598.76 | 643 / 653 | 94% | 24.46 | 571 / 605 |
prostate | 100% | 1883.27 | 244 / 245 | 93% | 24.42 | 466 / 502 |
skin | 97% | 2564.68 | 1751 / 1809 | 95% | 29.39 | 447 / 472 |
lung | 100% | 2040.86 | 576 / 578 | 91% | 34.40 | 1055 / 1155 |
kidney | 100% | 2388.46 | 89 / 89 | 89% | 21.98 | 805 / 901 |
ovary | 99% | 1375.87 | 178 / 180 | 90% | 33.71 | 387 / 430 |
pancreas | 89% | 743.71 | 293 / 328 | 97% | 48.83 | 173 / 178 |
breast | 100% | 2085.56 | 459 / 459 | 83% | 21.76 | 925 / 1118 |
brain | 86% | 740.28 | 2281 / 2642 | 75% | 12.22 | 526 / 705 |
adrenal gland | 98% | 2115.66 | 252 / 258 | 45% | 9.19 | 103 / 230 |
adipose | 100% | 2119.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 58.01 | 80 / 80 |
spleen | 100% | 2793.38 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 40.76 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 85.39 | 1 / 1 |
blood vessel | 98% | 1217.74 | 1314 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 2474.06 | 911 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 27.91 | 28 / 29 |
heart | 97% | 980.48 | 831 / 861 | 0% | 0 | 0 / 0 |
muscle | 89% | 866.07 | 712 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034355 | Biological process | NAD salvage |
GO_0006979 | Biological process | response to oxidative stress |
GO_0035578 | Cellular component | azurophil granule lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0005576 | Cellular component | extracellular region |
GO_0016740 | Molecular function | transferase activity |
GO_0004516 | Molecular function | nicotinate phosphoribosyltransferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | NAPRT |
Protein name | Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (FHA-HIT-interacting protein) (Nicotinate phosphoribosyltransferase domain-containing protein 1) Nicotinate phosphoribosyltransferase (EC 6.3.4.21) nicotinate phosphoribosyltransferase (EC 6.3.4.21) |
Synonyms | NAPRT1 hCG_32062 FHIP |
Description | FUNCTION: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate . Helps prevent cellular oxidative stress via its role in NAD biosynthesis . . FUNCTION: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis. . FUNCTION: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. . |
Accessions | ENST00000632139.1 [Q6XQN6-3] Q6XQN6 ENST00000460623.5 C9J8U2 ENST00000435154.7 ENST00000632636.1 ENST00000426292.7 [Q6XQN6-3] A0A087WUT5 G5E977 ENST00000525583.5 ENST00000632020.1 ENST00000621955.1 [Q6XQN6-1] H0YDA6 ENST00000532645.1 ENST00000340490.7 H0YF31 ENST00000633197.1 ENST00000632672.1 ENST00000449291.7 [Q6XQN6-1] |