NAPRT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034355Biological processNAD salvage
GO_0006979Biological processresponse to oxidative stress
GO_0035578Cellular componentazurophil granule lumen
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0016740Molecular functiontransferase activity
GO_0004516Molecular functionnicotinate phosphoribosyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameNAPRT
Protein nameNicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (FHA-HIT-interacting protein) (Nicotinate phosphoribosyltransferase domain-containing protein 1)
Nicotinate phosphoribosyltransferase (EC 6.3.4.21)
nicotinate phosphoribosyltransferase (EC 6.3.4.21)
SynonymsNAPRT1
hCG_32062
FHIP
DescriptionFUNCTION: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate . Helps prevent cellular oxidative stress via its role in NAD biosynthesis . .

FUNCTION: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis. .

FUNCTION: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. .

AccessionsENST00000632139.1 [Q6XQN6-3]
Q6XQN6
ENST00000460623.5
C9J8U2
ENST00000435154.7
ENST00000632636.1
ENST00000426292.7 [Q6XQN6-3]
A0A087WUT5
G5E977
ENST00000525583.5
ENST00000632020.1
ENST00000621955.1 [Q6XQN6-1]
H0YDA6
ENST00000532645.1
ENST00000340490.7
H0YF31
ENST00000633197.1
ENST00000632672.1
ENST00000449291.7 [Q6XQN6-1]