NANOS1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NANOS1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NANOS1 at tissue level.

III. Associated gene sets

GO_0098749Biological processcerebellar neuron development
GO_0001894Biological processtissue homeostasis
GO_0061157Biological processmRNA destabilization
GO_0010608Biological processpost-transcriptional regulation of gene expression
GO_0001558Biological processregulation of cell growth
GO_0048477Biological processoogenesis
GO_0016477Biological processcell migration
GO_0017148Biological processnegative regulation of translation
GO_0010631Biological processepithelial cell migration
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0030371Molecular functiontranslation repressor activity
GO_0008047Molecular functionenzyme activator activity
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameNANOS1
Protein nameNanos homolog 1 (NOS-1) (EC_Rep1a)
Nanos homolog 1
SynonymsNOS1
DescriptionFUNCTION: May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. .

AccessionsENST00000340087.5
ENST00000425699.3
Q5T9H5
Q8WY41