NAGPA | OmnibusX

Name	Number of supported studies	Average coverage
non-classical monocyte	3 studies	20% ± 5%	Explore
dendritic cell	3 studies	34% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of NAGPA at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	601.93	226 / 226	100%	11.18	406 / 406
stomach	100%	974.74	359 / 359	100%	11.64	286 / 286
skin	100%	928.48	1808 / 1809	100%	16.03	472 / 472
esophagus	100%	757.50	1443 / 1445	100%	8.62	183 / 183
intestine	100%	1076.81	965 / 966	100%	11.99	526 / 527
thymus	100%	880.74	652 / 653	100%	10.07	604 / 605
kidney	100%	995.17	89 / 89	100%	10.96	898 / 901
brain	100%	1557.93	2633 / 2642	100%	8.82	705 / 705
prostate	100%	877.73	245 / 245	100%	9.68	500 / 502
uterus	100%	782.29	170 / 170	99%	9.77	456 / 459
ovary	99%	526.87	179 / 180	100%	7.89	429 / 430
breast	100%	754.34	459 / 459	99%	8.87	1109 / 1118
adrenal gland	100%	884.97	257 / 258	99%	10.01	228 / 230
bladder	100%	852.52	21 / 21	99%	10.17	497 / 504
lung	98%	802.49	569 / 578	100%	9.64	1152 / 1155
pancreas	98%	431.63	323 / 328	99%	9.58	177 / 178
adipose	100%	795.51	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	12.09	80 / 80
lymph node	0%	0	0 / 0	100%	14.49	29 / 29
spleen	100%	1608.37	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	10.29	45 / 45
ureter	0%	0	0 / 0	100%	8.31	1 / 1
blood vessel	99%	591.95	1322 / 1335	0%	0	0 / 0
muscle	98%	413.89	785 / 803	0%	0	0 / 0
peripheral blood	97%	647.26	898 / 929	0%	0	0 / 0
heart	95%	404.90	815 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007040	Biological process	lysosome organization
GO_0033299	Biological process	secretion of lysosomal enzymes
GO_0005975	Biological process	carbohydrate metabolic process
GO_0036211	Biological process	protein modification process
GO_0006622	Biological process	protein targeting to lysosome
GO_0006486	Biological process	protein glycosylation
GO_0032580	Cellular component	Golgi cisterna membrane
GO_0016020	Cellular component	membrane
GO_0003944	Molecular function	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
GO_0005515	Molecular function	protein binding

Gene name	NAGPA
Protein name	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Synonyms
Description	FUNCTION: Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N-acetylglucosaminyltransferases. .
Accessions	ENST00000381955.7 [Q9UK23-2] ENST00000562037.1 K7EL75 K7EPH3 K7EK96 ENST00000565876.5 Q9UK23 ENST00000649828.1 [Q9UK23-3] ENST00000312251.8 [Q9UK23-1] ENST00000562746.5 [Q9UK23-3] K7EJ25 ENST00000563578.5 ENST00000569296.5 K7ERI4 ENST00000562346.2

NAGPA report